Dr. Yu-Shiuan Lin

PhD, Psychologist

My research interest is using neuroimaging methods to investigate the impacts of daily caffeine intake and acute caffeine withdrawal on cerebral structures, perfusion, and neurocognitive functions. In particular, I am using neurobehavioral model to examine in the caffeine effects on striatal dopamine signaling and functions through the adenosinergic modulation. In addition, I also looked into the potential impacts of daily caffeine intake on the pharmacokinetics of caffeine and its metabolites.

Publications

2024

Lin, Y. -S.; Lange, D.; Baur, D.; Foerge, A.; Elmenhorst, E. -M.; Neumaier, B.; Bauer, A.; Aeschbach, D.; Landolt, H. -P.; Elmenhorst, D.

Repeated caffeine intake suppresses cerebral grey matter responses to chronic sleep restriction in an A1 adenosine receptor-dependent manner: a double-blind randomized controlled study with PET-MRI Journal Article

In: Scientific Reports, vol. 14, iss. 1, pp. 12724, 2024.

Abstract | Links | BibTeX

2023

Lin, Y. -S.; Weibel, J.; Landolt, H. -P.; Santini, F.; Slawik, H.; Borgwardt, S.; Cajochen, C.; Reichert, C. F.

Brain activity during a working memory task after daily caffeine intake and caffeine withdrawal: a randomized double-blind placebo-controlled trial. Journal Article

In: Scientific Reports, vol. 13, iss. 1, no. 1002, 2023.

Abstract | Links | BibTeX

2022

Lin, Y. -S.; Weibel, J.; Landolt, H. -P.; Santini, F; Garbazza, C; Kistler, J; Rehm, S; Rentsch, K; Borgwardt, S; Cajochen, C; Reichert, C. F.

Time to recover from daily caffeine intake Journal Article

In: Front Nutr., vol. 8, no. 787225, 2022.

Links | BibTeX

2021

Weibel, J.; Lin, Y. -S.; Landolt, H. -P.; Berthomier, C.; Brandenwinder, M.; Kistler, J.; Rehm, S.; Rentsch, K.; Meyer, M.; Borgwardt, S.; Cajochen, C.; Reichert, C. F.

Regular caffeine intake delays REM sleep promotion and attenuates sleep quality in healthy men Journal Article

In: Journal of Biological Rhythms, 2021.

Abstract | Links | BibTeX

Lin, Y. -S.; Weibel, J.; Landolt, H.; Santini, F.; Meyer, M.; Brunmair, J.; Meyer-Menches, S.; gerner, C.; Borgwardt, S.; Cajochen, C.; Reichert, C. F.

Daily Caffeine Intake Induces Concentration-Dependent Medial Temporal Plasticity in Humans: A Multimodal Double-Blind Randomized Controlled Trial Journal Article

In: Cerebral Cortex, 2021.

Abstract | Links | BibTeX

2020

Reichert, C. F.; Veitz, S.; Bühler, M.; Gruber, G.; Deuring, G.; S. S. Rehm, K. Rentsch; Garbazza, C.; Meyer, M.; Slawik, H.; Lin, Y. -S.; Weibel, J.

Wide awake at bedtime? The effects of caffeine on sleep and circadian timing in teenagers - a randomized crossover trial. Journal Article

In: Biochemical Pharmacology, 2020.

Abstract | Links | BibTeX

Weibel, J.; Lin, Y. -S.; Landolt, H. -P.; Garbazza, C.; Kolodyazhniy, V.; Kistler, J.; Rehm, S.; Rentsch, K.; Borgwardt, S.; Cajochen, C.; Reichert, C. F.

Caffeine-dependent changes of sleep-wake regulation: Evidence foradaptation after repeated intake Journal Article

In: Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2020.

Abstract | Links | BibTeX

2019

Lin, Y. -S.; Fusar-Poli, P.; Borgwardt, S.

Neuroimaging and the At-Risk Mental State Book Chapter

In: Galderisi, Silvana; DeLisi, Lynn E; Borgwardt, Stefan (Ed.): Neuroimaging of Schizophrenia and Other Primary Psychotic Disorders : Achievements and Perspectives, pp. 219–265, Springer International Publishing, Cham, 2019, ISBN: 978-3-319-97307-4.

Abstract | Links | BibTeX