Prof. Dr. Christian Cajochen

Head Centre for Chronobiology, Biologist

Prof. Christian Cajochen is heading the Centre for Chronobiology at the University of Basel. He received his PhD in natural sciences from the ETH in Zürich, Switzerland, followed by a 3-y postdoctoral stay at the Harvard Medical School in Boston, USA. His major research interests include investigative work on the influence of light on human cognition, circadian rhythms and sleep, circadian related disturbances in psychiatric disorders, and age-related changes in the circadian regulation of sleep and neurobehavioral performance. He has held a number of honours and has authored more than 200 original papers and reviews in his career.

Publications

2022

Gimenez, M; Stefani, O; Cajochen, C; Lang, D; Deuring, G; Schlangen, L J M

Predicting melatonin suppression by light in humans: unifying photoreceptor-based equivalent daylight illuminances, spectral composition, timing and duration of light exposure Journal Article

Journal of Pineal Research, 2022.

Abstract | Links | BibTeX

2021

Spitschan, M; Garbazza, C; Kohl, S; Cajochen, C

Sleep and circadian phenotype in people without cone-mediated vision: a case series of five CNGB3 and two CNGA3 patients Journal Article

Brain Communications, 2021.

Abstract | Links | BibTeX

Weibel, J; Lin, Y -S; Landolt, H -P; Berthomier, C; Brandenwinder, M; Kistler, J; Rehm, S; Rentsch, K; Meyer, M; Borgwardt, S; Cajochen, C; Reichert, C F

Regular caffeine intake delays REM sleep promotion and attenuates sleep quality in healthy men Journal Article

Journal of Biological Rhythms, 2021.

Abstract | Links | BibTeX

Stefani, O; Cajochen, C

Should We Re-think Regulations and Standards for Lighting at Workplaces? A Practice Review on Existing Lighting Recommendations Journal Article

Frontiers in psychiatry, 12 , 2021.

Abstract | Links | BibTeX

Blume, C; Cajochen, C

‘SleepCycles’ package for R - A free software tool for the detection of sleep cycles from sleep staging Journal Article

MethodsX, 2021.

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Lin, Y -S; Weibel, J; Landolt, H; Santini, F; Meyer, M; Brunmair, J; Meyer-Menches, S; gerner, C; Borgwardt, S; Cajochen, C; Reichert, C F

Daily Caffeine Intake Induces Concentration-Dependent Medial Temporal Plasticity in Humans: A Multimodal Double-Blind Randomized Controlled Trial Journal Article

Cerebral Cortex, 2021.

Abstract | Links | BibTeX

2020

Stefani, O; Freyburger, M; Veitz, S; Basishvili, T; Meyer, M; Weibel, J; Kobayashi, K; Shirakawa, Y; Cajochen, C

Changing color and intensity of LED lighting across the day impacts on circadian melatonin rhythms and sleep in healthy men Journal Article

Journal of Pineal Research, 70 , 2020.

Links | BibTeX

Blume, C; Schmidt, Marlene H; Cajochen, C

Effects of the COVID-19 lockdown on human sleep and rest-activity rhythms Journal Article

Current Biology, 2020.

Abstract | Links | BibTeX

Eze, I C; Jeong, A; Schaffner, E; Rezwan, F I; Ghantous, A; Foraster, M; Vienneau, D; F, Kronenberg F; Herceg, Z; Vineis, P; Brink, M; Wunderli, J M; Schindler, C; Cajochen, C; M, Röösli M; Holloway, J W; Imboden, M; Probst-Hensch, N

Genome-Wide DNA Methylation in Peripheral Blood and Long-Term Exposure to Source-Specific Transportation Noise and Air Pollution: The SAPALDIA Study Journal Article

Environ Health Perspect, 128 (6), pp. 67003, 2020.

Links | BibTeX

Hollinger, A; von Felten, S; Sutter, R; Huber, J; Tran, F; Reinhold, S; Abdelhamid, S; Todorov, A; Gebhard, C E; Cajochen, C; Steiner, L A; Siegemund, M

Study Protocol for a Prospective Randomised Double-Blind Placebo-Controlled Clinical Trial Investigating a Better Outcome With Melatonin Compared to Placebo Administered to Normalize Sleep-Wake Cycle and Treat Hypoactive ICU Delirium: The Basel BOMP-AID Study Journal Article

BMJ Open, 2020.

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Weibel, J; Lin, Y -S; Landolt, H -P; Garbazza, C; Kolodyazhniy, V; Kistler, J; Rehm, S; Rentsch, K; Borgwardt, S; Cajochen, C; Reichert, C F

Caffeine-dependent changes of sleep-wake regulation: Evidence foradaptation after repeated intake Journal Article

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2020.

Abstract | Links | BibTeX

Chellappa, S L; Bromundt, V; Frey, S; Schlote, T; Goldblum, D; Cajochen, C; Reichert, C F

Intraocular cataract lens replacement and light exposure potentially impact procedural learning in older adults Journal Article

2020.

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Rudzik, F; Thiesse, L; Pieren, R; Héritier, H; Eze, I C; Foraster, M; Vienneau, D; Brink, M; Wunderli, J M; Probst-Hensch, N; Röösli, M; Fulda, S; Cajochen, C

Ultradian Modulation of Cortical Arousals During Sleep: Effects of Age and Exposure to Nighttime Transportation Noise Journal Article

Sleep, 2020.

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2019

Spitschan, M; Lazar, R; Yetik, E; Cajochen, C

No evidence for an S cone contribution to acute neuroendocrine and alerting responses to light Journal Article

Current Biology, 2019.

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Spitschan, M; Lazar, R; Cajochen, C

Visual and non-visual properties of filters manipulating short-wavelength light Journal Article

Ophthalmic Physiol Opt, 2019.

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2017

Gabel, V; Reichert, C F; Maire, M; Schmidt, C; Schlangen, L J M; Kolodyazhniy, V; Garbazza, C; Cajochen, C; Viola, A U

Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness Journal Article

Scientific Reports, 7 (7620), pp. doi:doi:10.1038/s41598-017-07060-8, 2017.

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Reichert, C F; Maire, M; Gabel, V; Viola, A U; Götz, T; Scheffler, K; Klarhöfer, M; Berthomier, C; Strobel, W; Phillips, C; Salmon, E; Cajochen, C; Schmidt, C

Cognitive brain responses during circadian wake-promotion: evidence for sleep-pressure-dependent hypothalamic activations Journal Article

Scientific Reports, 7 , pp. doi:10.1038/s41598-017-05695-1, 2017.

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2016

Reichert, C F; Maire, M; Schmidt, C; Cajochen, C

Sleep-wake regulation and its impact on working memory performance: the role of adenosine Journal Article

Biology, 5 (1), pp. E11. doi:10.3390/biology5010011., 2016.

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Garbazza, C; Bromundt, V; Eckert, A; Brunner, D P; Meier, F; Hackethal, S; Cajochen, C

Non-24-Hour Sleep-Wake Disorder Revisited - A Case Study Journal Article

Front Neurol. 2016 Feb 29;7:17 doi: 10.3389/fneur.2016.00017, 2016.

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2015

Schmidt, C; Collette, F; Reichert, C F; Maire, M; Vandewalle, G; Peigneux, P; Cajochen, C

Pushing the limits: chronotype and time of day modulate working memory-dependent cerebral activity Journal Article

Frontiers in Neurology, 25 (6:199), pp. 1-9, 2015.

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Gabel, V; Maire, M; Reichert, C F; Chellappa, S L; Schmidt, C; Hommes, V; Cajochen, C; Viola, A U

Dawn simulation light impacts on different cognitive domains under sleep restriction Journal Article

Behav Brain Res., doi: 10.1016/j.bbr.2014.12.043, 15 , pp. 281: 258-266, 2015.

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Maire, M; Reichert, C F; Gabel, V; Viola, A U; Phillips, C; Krebs, J; Scheffler, K; Klarhöfer, M; Strobel, W; Cajochen, C; Schmidt, C

Fighting Sleep at Night: Brain Correlates and Vulnerability to Sleep Loss Journal Article

Ann Neurol., doi: 10.1002/ana.24434., 78(2) , pp. 235-247, 2015.

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vanderLely, S; Frey, S; Garbazza, C; Wirz-Justice, A; Jenni, O G; Steiner, R; Wolf, S; Cajochen, C; Bromundt, V; Schmidt, C

Blue blocker glasses as a countermeasure for alerting effects of evening light-emitting diode screen exposure in male teenagers Journal Article

J Adolesc Health, doi: 10.1016/j.jadohealth.2014.08.002, 56(1) , pp. 113-119, 2015.

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2014

Reichert, C F; Maire, M; Gabel, V; Hofstetter, M; Viola, A U; Kolodyazhniy, V; Strobel, W; Goetz, T; V. Bachmann, ; Landolt, H -P; Cajochen, C; Schmidt, C

The Circadian Regulation of Sleep: Impact of a Functional ADA-Polymorphism and Ist Association to Working Memory Journal Article

PLoS ONE, 9 (12), pp. 1-23, 2014.

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Chellappa, S L; Viola, A U; Schmidt, C; Bachmann, V; Gabel, V; Maire, M; Reichert, C F; Valomon, A; Landolt, H P; Cajochen, C

Light modulation of human sleep depends on a polymorphism in the clock gene Period3 Journal Article

Behavioural Brain Research, 271 , pp. 23-29, 2014.

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Reichert, C F; Maire, M; Gabel, V; Viola, A U; Kolodyazhniy, V; Strobel, W; Götz, T; Bachmann, V; Landolt, H P; Cajochen, C; Schmidt, C

Insights into Behavioral Vulnerability to Differential Sleep Pressure and Circadian Phase from a Functional ADA Polymorphism Journal Article

Journal of Biological Rhythms, 29 (2), pp. 119-130, 2014.

Abstract | Links | BibTeX

Maire, M; Reichert, C F; Gabel, V; Viola, A U; Krebs, J; Strobel, W; Landolt, H P; Bachmann, V; Cajochen, C; Schmidt, C

Time-on-task decrement in vigilance is modulated by inter-individual vulnerability to homeostatic sleep pressure manipulation Journal Article

Frontiers in Behavioral Neuroscience, 8 (59), 2014, ISSN: 1662-5153.

Abstract | Links | BibTeX

Maire, M; Reichert, C F; Gabel, V; Viola, A U; Strobel, W; Krebs, J; Landolt, H P; Bachmann, V; Cajochen, C; Schmidt, C

Sleep ability mediates individual differences in the vulnerability to sleep loss: Evidence from a PER3 polymorphism Journal Article

Cortex, http://dx.doi.org/10.1016/j.cortex.2013. , 2014.

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2013

Gabel, V; Maire, M; Reichert, C F; Chellappa, S L; Schmidt, C; Hommes, V; Viola, A U; Cajochen, C

Effects of Artificial Dawn and Morning Blue Light on Daytime Cognitive Performance, Well-being, Cortisol and Melatonin Levels Journal Article

Chronobiology International, 30 , pp. 988-97, 2013.

Abstract | Links | BibTeX

2011

Chellappa, S L; Viola, A U; Schmidt, C; Bachmann, V; Gabel, V; Maire, M; Reichert, C F; Valomon, A; Götz, T; Landolt, H P; Cajochen, C

Human melatonin and alerting response to blue-enriched light depend on a polymorphism in the clock gene PER3 Journal Article

J Clin Endocrinol Metab 97(3), 2011.

Links | BibTeX