Prof. Dr. Christian Cajochen

Head Centre for Chronobiology

Prof. Christian Cajochen is heading the Centre for Chronobiology at the University of Basel. He received his PhD in natural sciences from the ETH in Zürich, Switzerland, followed by a 3-y postdoctoral stay at the Harvard Medical School in Boston, USA. His major research interests include investigative work on the influence of light on human cognition, circadian rhythms and sleep, circadian related disturbances in psychiatric disorders, and age-related changes in the circadian regulation of sleep and neurobehavioral performance. He has held a number of honours and has authored more than 200 original papers and reviews in his career.

Publications

2020

Blume, C; Schmidt, Marlene H; Cajochen, C

Effects of the COVID-19 lockdown on human sleep and rest-activity rhythms Journal Article

Current Biology, 2020.

Abstract | Links | BibTeX

Eze, I C; Jeong, A; Schaffner, E; Rezwan, F I; Ghantous, A; Foraster, M; Vienneau, D; F, Kronenberg F; Herceg, Z; Vineis, P; Brink, M; Wunderli, J M; Schindler, C; Cajochen, C; M, Röösli M; Holloway, J W; Imboden, M; Probst-Hensch, N

Genome-Wide DNA Methylation in Peripheral Blood and Long-Term Exposure to Source-Specific Transportation Noise and Air Pollution: The SAPALDIA Study Journal Article

Environ Health Perspect, 128 (6), pp. 67003, 2020.

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Hollinger, A; von Felten, S; Sutter, R; Huber, J; Tran, F; Reinhold, S; Abdelhamid, S; Todorov, A; Gebhard, C E; Cajochen, C; Steiner, L A; Siegemund, M

Study Protocol for a Prospective Randomised Double-Blind Placebo-Controlled Clinical Trial Investigating a Better Outcome With Melatonin Compared to Placebo Administered to Normalize Sleep-Wake Cycle and Treat Hypoactive ICU Delirium: The Basel BOMP-AID Study Journal Article

BMJ Open, 2020.

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Weibel, J; Lin, Y; Landolt, H; Garbazza, C; Kolodyazhniy, V; Kistler, J; Rehm, S; Rentsch, K; Borgwardt, S; Cajochen, C; Reichert, C F

Caffeine-dependent changes of sleep-wake regulation: evidence for adaptation after repeated intake Journal Article

Prog Neuropsychopharmacol Biol Psychiatry, 2020.

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Chellappa, S L; Bromundt, V; Frey, S; Schlote, T; Goldblum, D; Cajochen, C; Reichert, C F

Intraocular cataract lens replacement and light exposure potentially impact procedural learning in older adults Journal Article

2020.

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Rudzik, F; Thiesse, L; Pieren, R; Héritier, H; Eze, I C; Foraster, M; Vienneau, D; Brink, M; Wunderli, J M; Probst-Hensch, N; Röösli, M; Fulda, S; Cajochen, C

Ultradian Modulation of Cortical Arousals During Sleep: Effects of Age and Exposure to Nighttime Transportation Noise Journal Article

Sleep, 2020.

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2019

Cajochen, C; Reichert, C; Maire, M; Schlangen, L J M; Schmidt, C; Viola, A U; Gabel, V

Evidence That Homeostatic Sleep Regulation Depends on Ambient Lighting Conditions during Wakefulness Journal Article

Clocks & Sleep, 2019.

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Garbazza, C; Hackethal, S; Riccardi, S; Cajochen, C; Cicolin, A; D'Agostino, A; Cirignotta, F; Manconi, M

Polysomnographic features of pregnancy: A systematic review Journal Article

Sleep Med Rev., 2019.

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Spitschan, M; Lazar, R; Cajochen, C

Visual and non-visual properties of filters manipulating short-wavelength light Journal Article

Ophthalmic Physiol Opt, 2019.

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Spitschan, M; Cajochen, C

Binocular facilitation in light-mediated melatonin suppression? Journal Article

J Pineal Res, 2019.

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Brink, M; Schäffer, B; Vienneau, D; Pieren, R; Foraster, M; Eze, I C; Rudzik, F; Thiesse, L; Cajochen, C; Probst-Hensch, N; Röösli, M; JM24., Wunderli J M

Self-Reported Sleep Disturbance from Road, Rail and Aircraft Noise: Exposure-Response Relationships and Effect Modifiers in the SiRENE Study Journal Article

Environ Int, 2019.

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Röösli, M; Brink, M; Rudzik, F; Cajochen, C; Ragettli, M S; Flückiger, B; Pieren, R; Vienneau, D; Wunderli, J -M

Associations of Various Nighttime Noise Exposure Indicators with Objective Sleep Efficiency and Self-Reported Sleep Quality: A Field Study Journal Article

Environ Int, 2019.

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Gaig, C; Iranzo, A; Cajochen, C; Vilaseca, I; Embid, C; Dalmau, J; Graus, F; Santamaria, J

Characterization of the sleep disorder of anti-IgLON5 disease. Journal Article

Sleep, 2019.

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Chellappa, SL.; Bromundt, V; Frey, S; Steinemann, A; Schmidt, C; Schlote, T; Goldblum, D; Cajochen, C

Association of Intraocular Cataract Lens Replacement With Circadian Rhythms, Cognitive Function, and Sleep in Older Adults Journal Article

JAMA Ophthalmol, 2019.

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Zhang, Z; Cajochen, C; Khatami, R

Social Jetlag and Chronotypes in the Chinese Population: Analysis of Data Recorded by Wearable Devices Journal Article

J Med Internet Res, 2019.

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Knaier, R; Niemeyer, M; Wagner, J; Infanger, D; Hinrichs, T; Klenk, C; Frutig, S; Cajochen, C; Schmidt-Trucksäss, A

Which Cutoffs for Secondary V˙O2max Criteria Are Robust to Diurnal Variations? Journal Article

Med Sci Sports Exerc., 2019.

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Brink, M; Schäffer, B; Vienneau, D; Foraster, M; Pieren, R; Eze, IC.; Cajochen, C; Probst-Hensch, N; Röösli, M; Wunderli, JM.

A survey on exposure-response relationships for road, rail, and aircraft noise annoyance: Differences between continuous and intermittent noise. Journal Article

Environ Int, 2019.

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Steinemann, A; Bromundt, V; Chellappa, SL.; Frey, S; Schmidt, C; Schlote, T; Goldblum, D; Cajochen, C

Evaluation of Visual Comfort and Mental Effort Under Different Light Conditions for Ultraviolet-Absorbing and Additional Blue-Filtering Intraocular Lenses for Cataract Surgery. Journal Article

Klin Monbl Augenheilkd., 2019.

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Cajochen, C; Freyburger, M; Basishvili, T; Garbazza, C; Rudzik, F; Renz, C; Kobayashi, K; Shirakawa, Y; Stefani, O; Weibel, J

Effect of daylight LED on visual comfort, melatonin, mood, waking performance and sleep Journal Article

2019.

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Knaier, R; Infanger, D; Niemeyer, M; Cajochen, C; Schmidt-Trucksäss, A

In Athletes, the Diurnal Variations in Maximum Oxygen Uptake Are More Than Twice as Large as the Day-to-Day Variations. Journal Article

Front Physiol., 2019.

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Vienneau, D; Héritier, H; Foraster, M; Eze, IC.; Schaffner, E; Thiesse, L; Rudzik, F; Habermacher, M; Köpfli, M; Pieren, R; Brink, M; Cajochen, C; Wunderli, JM.; Probst-Hensch, N; Röösli, M; study group, SNC

Façades, floors and maps - Influence of exposure measurement error on the association between transportation noise and myocardial infarction. Journal Article

Environ Int., 2019.

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Héritier, H; Vienneau, D; Foraster, M; Eze, IC.; Schaffner, E; de Hoogh, K; Thiesse, L; Rudzik, F; Habermacher, M; Köpfli, M; Pieren, R; Brink, M; Cajochen, C; Wunderli, JM.; Probst-Hensch, N; Röösli, M

A systematic analysis of mutual effects of transportation noise and air pollution exposure on myocardial infarction mortality: a nationwide cohort study in Switzerland. Journal Article

Eur Heart J., 2019.

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Schneeberger, AR.; Seixas, A; Schweinfurth, N; Lang, UE.; Cajochen, C; Bux, DA.; Richards, S; Jean-Louis, ; Huber, CG.

Differences in Insomnia Symptoms between Immigrants and Non-Immigrants in Switzerland attributed to Emotional Distress: Analysis of the Swiss Health Survey. Journal Article

Int J Environ Res Public Health, 2019.

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2018

Thiesse, L; Rudzik, F; Spiegel, K; Leproult, R; Pieren, R; Wunderli, JM.; Foraster, M; Héritier, H; Eze, IC.; Meyer, M; Vienneau, D; Brink, M; Probst-Hensch, N; Röösli, M; Cajochen, C

Adverse impact of nocturnal transportation noise on glucose regulation in healthy young adults: Effect of different noise scenarios. Journal Article

Environ Int., 2018.

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Khan, S; Nobili, L; Khatami, R; Loddenkemper, T; Cajochen, C; Dijk, DJ.; Eriksson, SH.

Circadian rhythm and epilepsy. Journal Article

Lancet Neurol., 2018.

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Foraster, M; Eze, IC.; Vienneau, D; Schaffner, E; Jeong, A; Héritier, H; Rudzik, F; Thiesse, L; Pieren, R; Brink, M; Cajochen, C; Wunderli, JM.; Röösli, M; Probst-Hensch, N

Long-term exposure to transportation noise and its association with adiposity markers and development of obesity. Journal Article

Environ Int., 2018.

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Eze, IC.; Foraster, M; Schaffner, E; Vienneau, D; Héritier, H; Pieren, R; Thiesse, L; Rudzik, F; Rothe, T; Pons, M; Bettschart, R; Schindler, C; Cajochen, C; Wunderli, JM.; Brink, M; Röösli, M; Probst-Hensch, N

Transportation noise exposure, noise annoyance and respiratory health in adults: A repeated-measures study. Journal Article

Environ Int., 2018.

Links | BibTeX

Lasauskaite, R; Hazelhoff, E M; Cajochen, C

Four minutes might not be enough for color temperature of light to affect subjective sleepiness, mental effort, and light ratings Journal Article

Lighting Research & Technology, pp. doi: 10.1177/1477153518796700, 2018.

BibTeX

van der Meijden, WP.; Lindert, BHW. Te; Ramautar, JR.; Wei, Y; Coppens, JE.; Kamermans, M; Cajochen, C; Someren, Bourgin EJW. Van P

Sustained effects of prior red light on pupil diameter and vigilance during subsequent darkness. Journal Article

Proc Biol Sci., 2018.

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Rudzik, F; Thiesse, L; Pieren, R; Wunderli, J M; Brink, M; Foraster, M; Héritier, H; Exe, I C; Garbazza, C; Vienneau, D; Probst-Hensch, N; Röösli, M; Cajochen, C

Sleep spindle characteristics and arousability from nighttime transportation noise exposure in healthy young and older individuals. Journal Article

Sleep, 41 (7), pp. doi: 10.1093/sleep/zsy077, 2018.

BibTeX

Lasauskaite, R; Cajochen, C

Influence of lighting color temperature on effort-related cardiac response Journal Article

Biological Psychology, 132 , pp. doi:10.1016/j.biopsycho.2017.11.005, 2018.

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Maire, M; Reichert, C F; Gabel, V; Viola, A U; Phillips, C; Berthomier, C; Borgwardt, S; Cajochen, C; Schmidt, C

Human brain patterns underlying vigilant attention: impact of sleep debt, circadian phase and attentional engagement. Journal Article

Scientific Reports, pp. doi: 10.1038/s41598-017-17022-9, 2018.

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2017

Gabel, V; Reichert, C F; Maire, M; Schmidt, C; Schlangen, L J M; Kolodyazhniy, V; Garbazza, C; Cajochen, C; Viola, A U

Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness Journal Article

Scientific Reports, 7 (7620), pp. doi:doi:10.1038/s41598-017-07060-8, 2017.

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Reichert, C F; Maire, M; Gabel, V; Viola, A U; Götz, T; Scheffler, K; Klarhöfer, M; Berthomier, C; Strobel, W; Phillips, C; Salmon, E; Cajochen, C; Schmidt, C

Cognitive brain responses during circadian wake-promotion: evidence for sleep-pressure-dependent hypothalamic activations Journal Article

Scientific Reports, 7 , pp. doi:10.1038/s41598-017-05695-1, 2017.

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2016

Baiardi, S; Cirignotta, F; Cicolin, A; Garbazza, C; D'Agostino, A; Gambini, O; Giordano, A; Canevini, M; Zambrelli, E; Marconi, A M; Mondini, S; Borgwardt, S; Cajochen, C; Rizzo, N; Manconi, M

Chronobiology, sleep-related risk factors and light therapy in perinatal depression: the "Life-ON" project Journal Article

BMC Psychiatry, 16 , pp. doi:10.1186/s12888-016-1086-0, 2016.

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Reichert, C F; Maire, M; Schmidt, C; Cajochen, C

Sleep-wake regulation and its impact on working memory performance: the role of adenosine Journal Article

Biology, 5 (1), pp. E11. doi:10.3390/biology5010011., 2016.

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Garbazza, C; Bromundt, V; Eckert, A; Brunner, D P; Meier, F; Hackethal, S; Cajochen, C

Non-24-Hour Sleep-Wake Disorder Revisited - A Case Study Journal Article

Front Neurol. 2016 Feb 29;7:17 doi: 10.3389/fneur.2016.00017, 2016.

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2015

Schmidt, C; Collette, F; Reichert, C F; Maire, M; Vandewalle, G; Peigneux, P; Cajochen, C

Pushing the limits: chronotype and time of day modulate working memory-dependent cerebral activity Journal Article

Frontiers in Neurology, 25 (6:199), pp. 1-9, 2015.

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Gabel, V; Maire, M; Reichert, C F; Chellappa, S L; Schmidt, C; Hommes, V; Cajochen, C; Viola, A U

Dawn simulation light impacts on different cognitive domains under sleep restriction Journal Article

Behav Brain Res., doi: 10.1016/j.bbr.2014.12.043, 15 , pp. 281: 258-266, 2015.

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Maire, M; Reichert, C F; Gabel, V; Viola, A U; Phillips, C; Krebs, J; Scheffler, K; Klarhöfer, M; Strobel, W; Cajochen, C; Schmidt, C

Fighting Sleep at Night: Brain Correlates and Vulnerability to Sleep Loss Journal Article

Ann Neurol., doi: 10.1002/ana.24434., 78(2) , pp. 235-247, 2015.

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vanderLely, S; Frey, S; Garbazza, C; Wirz-Justice, A; Jenni, O G; Steiner, R; Wolf, S; Cajochen, C; Bromundt, V; Schmidt, C

Blue blocker glasses as a countermeasure for alerting effects of evening light-emitting diode screen exposure in male teenagers Journal Article

J Adolesc Health, doi: 10.1016/j.jadohealth.2014.08.002, 56(1) , pp. 113-119, 2015.

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2014

Reichert, C F; Maire, M; Gabel, V; Hofstetter, M; Viola, A U; Kolodyazhniy, V; Strobel, W; Goetz, T; V. Bachmann, ; Landolt, H -P; Cajochen, C; Schmidt, C

The Circadian Regulation of Sleep: Impact of a Functional ADA-Polymorphism and Ist Association to Working Memory Journal Article

PLoS ONE, 9 (12), pp. 1-23, 2014.

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Chellappa, S L; Viola, A U; Schmidt, C; Bachmann, V; Gabel, V; Maire, M; Reichert, C F; Valomon, A; Landolt, H P; Cajochen, C

Light modulation of human sleep depends on a polymorphism in the clock gene Period3 Journal Article

Behavioural Brain Research, 271 , pp. 23-29, 2014.

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Reichert, C F; Maire, M; Gabel, V; Viola, A U; Kolodyazhniy, V; Strobel, W; Götz, T; Bachmann, V; Landolt, H P; Cajochen, C; Schmidt, C

Insights into Behavioral Vulnerability to Differential Sleep Pressure and Circadian Phase from a Functional ADA Polymorphism Journal Article

Journal of Biological Rhythms, 29 (2), pp. 119-130, 2014.

Abstract | Links | BibTeX

Maire, M; Reichert, C F; Gabel, V; Viola, A U; Krebs, J; Strobel, W; Landolt, H P; Bachmann, V; Cajochen, C; Schmidt, C

Time-on-task decrement in vigilance is modulated by inter-individual vulnerability to homeostatic sleep pressure manipulation Journal Article

Frontiers in Behavioral Neuroscience, 8 (59), 2014, ISSN: 1662-5153.

Abstract | Links | BibTeX

Maire, M; Reichert, C F; Gabel, V; Viola, A U; Strobel, W; Krebs, J; Landolt, H P; Bachmann, V; Cajochen, C; Schmidt, C

Sleep ability mediates individual differences in the vulnerability to sleep loss: Evidence from a PER3 polymorphism Journal Article

Cortex, http://dx.doi.org/10.1016/j.cortex.2013. , 2014.

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2013

Gabel, V; Maire, M; Reichert, C F; Chellappa, S L; Schmidt, C; Hommes, V; Viola, A U; Cajochen, C

Effects of Artificial Dawn and Morning Blue Light on Daytime Cognitive Performance, Well-being, Cortisol and Melatonin Levels Journal Article

Chronobiology International, 30 , pp. 988-97, 2013.

Abstract | Links | BibTeX

2011

Chellappa, S L; Viola, A U; Schmidt, C; Bachmann, V; Gabel, V; Maire, M; Reichert, C F; Valomon, A; Götz, T; Landolt, H P; Cajochen, C

Human melatonin and alerting response to blue-enriched light depend on a polymorphism in the clock gene PER3 Journal Article

J Clin Endocrinol Metab 97(3), 2011.

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