Prof. Dr. Christian Cajochen

Cajochen, C.

Head Centre for Chronobiology


Short-Biography:Prof. Christian Cajochen is heading the Centre for Chronobiology at the University of Basel. He received his PhD in natural sciences from the ETH in Zürich, Switzerland, followed by a 3-y postdoctoral stay at the Harvard Medical School in Boston, USA. His major research interests include investigative work on the influence of light on human cognition, circadian rhythms and sleep, circadian related disturbances in psychiatric disorders, and age-related changes in the circadian regulation of sleep and neurobehavioral performance. He has held a number of honours and has authored more than a 100 original papers and reviews in his career.

Email: Christian.Cajochen@upkbs.ch

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Publications by Christian Cajochen

Probst-Hensch, M. FOraster, I.C. Eze, D. Vienneau, M. Brink, C. Cajochen, S. Caviezel, H. Héritier, E. Schaffner, C. Schindler, M Wanner, J.-M. Wunderli, M. Röösli, N.

Long-term transportation noise annoyance is associated with subsequent lower levels of physical activity

Environment International, 91, pp. 341-349, 2016.

(BibTeX)

Bernsmeier, C.; Weisskopf, D.M.; Pflueger, M.O.; Mosimann, J.; Campana, C. B.; Terracciano, L.; Beglinger, C.; Heim, M. H.; Cajochen, C.

Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver Disease: A Comparison with Healthy Controls

PlosOne, DOI:10.1371/journal.pone.0143293, pp. 1-16, 2015.

(PDF & Links | BibTeX)

Schmidt, C.; Collette, F.; Reichert, C.F.; Maire, M.; Vandewalle, G.; Peigneux, P.; Cajochen, C.

Pushing the limits: chronotype and time of day modulate working memory-dependent cerebral activity

Frontiers in Neurology, 25 (6:199), pp. 1-9, 2015.

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Wunderli, J.M.; Pieren, R.; Habermacher, M.; Vienneau, D.; Cajochen, C.; Probst-Hensch, N.; Röösli, M.; Brink, M.

Intermittency ratio: A metric reflecting short-term temporal variations of transportation noise exposure

Journal of Exposure Science and Environmental Epidemiology, 9 September 2015; doi:10.1038/jes.2015.5, pp. 1-11, 2015.

(PDF & Links | BibTeX)

Knaier, R.; Meister, S.; Aeschbacher, T.; Gemperle, D.; Rossmeissl, A.; Cajochen, C.; Schmidt-Trucksäss, A.

Dose-response relationship between light exposure and cycling performance

Scand J Med Sci Sports, doi: 10.1111/sms.12535., 2015.

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Bassetti, C. L.; Ferini-Strambi, L.; Brown, S.; Adamantidis, A.; Benedetti, F.; Bruni, O.; Dolenc-Groselj, C. Cajochen and L.; Ferri, R.; Gais, S.; Huber, R.; Khatami, R.; Lammers, G. J.; Luppi, P. H.; Manconi, M.; Nissen, C.; Nobili, L.; Peigneux, P.; Pollmächer, T.; Randerath, W.; Riemann, D.; Santamaria, J.; Schindler, K.; Tafti, M.; Someren, E. Van; Wetter, T. C.

Neurology and psychiatry: waking up to opportunities of sleep. : State of the art and clinical/research priorities for the next decade

Eur J Neurol., doi: 10.1111/ene.12781., 2015.

(PDF & Links | BibTeX)

Meijden, W. P. van der; Lindert, B. H.W. te; Bijlenga, D.; Coppens, J. E.; Gomez-Herrero, G.; Bruijel, J.; Kooij, J.J. S.; Bourgin, C. Cajochen and P.; Someren, E. J.W. Van

Post-illumination pupil response after blue light: Reliability of optimized melanopsin-based phototransduction assessment

Exp Eye Res., doi: 10.1016/j.exer.2015.07.010, 139, pp. 73-80, 2015.

(PDF & Links | BibTeX)

Maire, M.; Reichert, C.; Gabel, V.; Viola, A. U.; Phillips, C.; Krebs, J.; Scheffler, K.; Klarhöfer, M.; Strobel, W.; Cajochen, C.; Schmidt, C.

Fighting Sleep at Night: Brain Correlates and Vulnerability to Sleep Loss

Ann Neurol., doi: 10.1002/ana.24434., 78(2), pp. 235-247, 2015.

(PDF & Links | BibTeX)

Viola, A. U.; Gabel, V.; Chellappa, S. L.; Schmidt, C.; Hommes, V.; Tobaldini, E.; Montano, N.; Cajochen, C.

Dawn simulation light: a potential cardiac events protector

Sleep Med., doi: 10.1016/j.sleep.2014.12.016, 16(4), pp. 457-461, 2015.

(PDF & Links | BibTeX)

Buttgereit, F.; Smolen, J. S.; Coogan, A. N.; Cajochen, C.

Clocking in: chronobiology in rheumatoid arthritis

Nature Reviews Rheumatology, doi:10.1038/nrrheum.2015.31, 11, pp. 349–356, 2015.

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Gabel, V.; Maire, M.; Reichert, C. F.; Chellappa, S. L.; Schmidt, C.; Hommes, V.; Cajochen, C.; Viola, A. U.

Dawn simulation light impacts on different cognitive domains under sleep restriction

Behav Brain Res., doi: 10.1016/j.bbr.2014.12.043, 15, pp. 281: 258-266, 2015.

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Lely, S. van der; Frey, S.; Garbazza, C.; Wirz-Justice, A.; Jenni, O. G.; Steiner, R.; Wolf, S.; Cajochen, C.; Bromundt, V.; Schmidt, C.

Blue blocker glasses as a countermeasure for alerting effects of evening light-emitting diode screen exposure in male teenagers

J Adolesc Health, doi: 10.1016/j.jadohealth.2014.08.002, 56(1), pp. 113-119, 2015.

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Burkhalter, H.; Wirz-Justice, A.; Denhaerynck, K.; Fehr, T.; Steiger, J.; Venzin, R. M.; Cajochen, C.; Weaver, T. E.; Geest, S. De

The effect of bright light therapy on sleep and circadian rhythms in renal transplant recipients: a pilot randomized, multicentre wait-list controlled trial.

Transpl Int., doi: 10.1111/tri.12443, 28(1), pp. 59-70, 2015.

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Cajochen, C.

Light: An underestimated environmental factor in sleep medicine

Sleep and Biological Rhythms, 13 (2), pp. 111, 2015.

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Reichert, C. F.; Maire, M.; Gabel, V.; Hofstetter, M.; Viola, A.U.; Kolodyazhniy, V.; Strobel, W.; Goetz, T.; V. Bachmann, ; Landolt, H.-P.; Cajochen, C.; Schmidt, C.

The Circadian Regulation of Sleep: Impact of a Functional ADA-Polymorphism and Ist Association to Working Memory

PLoS ONE, 9 (12), pp. 1-23, 2014.

(PDF & Links | BibTeX)

Cajochen, C.

Editorial: Tag-Wach & Nacht-Schlaf: Regulation, Störungen und Behandlung

Therapeutische Umschau, 71 (11), pp. 629, 2014.

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Tinguely, G.; Landolt, H-P.; Cajochen, C.

Schlafgewohnheiten, Schlafqualität und Schlafmittelkonsum der Schweizer Bevölkerung: Ergebnisse aus einer neuen Umfrage bei einer repräsentativen Stichprobe

Therapeutische Umschau, 71 (11), pp. 637-646, 2014.

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Cajochen, C.; Altanay-Ekici, S.; Münch, M.; Frey, S.; Knoblauch, V.; Wirz-Justice, A.

Reply to Cordi et al.

Current Biology, 24 (17), pp. R795, 2014.

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H, H. Burkhalter; Wirz-Justice, A.; Denhaerynck, K.; Fehr, T.; Steiger, J.; Venzin, R.M.; Cajochen, C.; Weaver, T.E.; Geest, S. De

The effect of bright light therapy on sleep and circadian rhythms in renal transplant recipients: a pilot randomized, multicentre wait-list controlled trial

Transpl Int., doi: 10.1111/tri.12443. [Epub ahead of p, 2014.

(PDF & Links | BibTeX)

Najjar, R.P.; Wolf, L.; Taillard, J.; Schlangen, L.J.; Salam, A.; Cajochen, C.; Gronfier., C.

Chronic artificial blue-enriched white light is an effective countermeasure to delayed circadian phase and neurobehavioral decrements

PLoS One. 2014 Jul 29;9(7):e102827. doi: 10.1371/journal.pone.0102827. eCollection 2014., 9 (7), pp. 1-10, 2014.

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Chellappa, S.L.; Viola, A.U.; Schmidt, C.; Bachmann, V.; Gabel, V.; Maire, M.; Reichert, C.F.; Valomon, A.; Landolt, H.P.; Cajochen, C.

Light modulation of human sleep depends on a polymorphism in the clock gene Period3

Behavioural Brain Research, 271, pp. 23-29, 2014.

(PDF & Links | BibTeX)

Reichert, C. F.; Maire, M.; Gabel, V.; Viola, A.U.; Kolodyazhniy, V.; Strobel, W.; Götz, T.; Bachmann, V.; Landolt, H.P.; Cajochen, C.; Schmidt, C.

Insights into Behavioral Vulnerability to Differential Sleep Pressure and Circadian Phase from a Functional ADA Polymorphism

Journal of Biological Rhythms, 29 (2), pp. 119-130, 2014.

(Abstract | PDF & Links | BibTeX)

Valomon, A.; Holst, S.C.; Bachmann, V.; Viola, A.U.; Schmidt, C.; Zürcher, J.; Berger, W.; Cajochen, C.; Landolt, H.P.

Genetic polymorphisms of DAT1 and COMT differentially associate with actigraphy-derived sleep-wake cycles in young adults

Chronobiology International, 2014 Mar 13. [Epub ahead of print], 2014.

(PDF & Links | BibTeX)

Maire, M.; Reichert, C.F.; Gabel, V.; Viola, A.U.; Krebs, J.; Strobel, W.; Landolt, H.P.; Bachmann, V.; Cajochen, C.; Schmidt, C.

Time-on-task decrement in vigilance is modulated by inter-individual vulnerability to homeostatic sleep pressure manipulation

Frontiers in Behavioral Neuroscience, 8 (59), 2014, ISSN: 1662-5153.

(Abstract | PDF & Links | BibTeX)

Winzeler, K.; Voellmin, A.; Schäfer, V.; A.H.Meyer, ; Cajochen, C.; Wilhelm, F.H.; Bader, K.

Daily stress, presleep arousal, and sleep in healthy young women: a daily life computerized sleep diary and actigraphy study

Sleep Medicine, 15 (3), pp. 359-366., 2014.

(PDF & Links | BibTeX)

Maire, M.; Reichert, C.F.; Gabel, V.; Viola, A.U.; Strobel, W.; Krebs, J.; Landolt, H.P.; Bachmann, V.; Cajochen, C.; Schmidt, C.

Sleep ability mediates individual differences in the vulnerability to sleep loss: Evidence from a PER3 polymorphism

Cortex, http://dx.doi.org/10.1016/j.cortex.2013., 2014.

(PDF & Links | BibTeX)

Burkhalter, H.; Wirz-Justice, A.; Cajochen, C.; Weaver, T.E.; Steiger, J.; Fehr, T.; Venzin, R. M.; Geest, S. De

Daytime sleepiness in renal transplant recipients is associated with immunosuppressive non-adherence: a cross-sectional, multi-center study

Clin Transplant, doi: 10.1111/ctr.12279., 2013.

(PDF & Links | BibTeX)

Danilenko, K. V.; Verevkin, E.G.; Antyufeev, V.S.; Wirz-Justice, A.; Cajochen, C.

The hockey-stick method to estimate evening dim light melatonin onset

Chronobiology International, early online, pp. 1-7, 2013.

(Abstract | PDF & Links | BibTeX)

Bromundt, V.; Frey, S.; Odermatt, J.; Cajochen, C.

Extraocular light via the ear canal does not acutely affect human circadian physiology, alertness and psychomotor vigilance performance

Chronobiology International, early online, pp. 1-6, 2013.

(Abstract | PDF & Links | BibTeX)

Putilov, A.A.; Münch, M.Y.; Cajochen, C.

Principal component structuring of the Non-REM sleep EEG spectrum in older adults yields age-related changes in the sleep and wake drives

Current Aging Science, 6 epub ahead, pp. 1-13, 2013.

(Abstract | PDF & Links | BibTeX)

Burkhalter, H.; Wirz-Justice, A.; Cajochen, C.; Weaver, T.E.; Steiger, J.; Fehr, T.; Venzin, R. M.; Geest, S. De

Validation of a single item to assess daytime sleepiness for the Swiss Transplant Cohort Study

Progress in Transplantation, 23 (3), pp. 1-9, 2013.

(Abstract | PDF & Links | BibTeX)

Burkhalter, H.; Brunner, D.P.; Wirz-Justice, A.; Cajochen, C.; Weaver, T.E.; Steiger, J.; Fehr, T.; Venzin, R. M.; Geest, S. De

Self-reported sleep disturbances in renal transplant recipients

BMC Nephrology, 14 (220), pp. 1-12, 2013.

(Abstract | PDF & Links | BibTeX)

Cajochen, C.; Altanay-Ekici, S.; Münch, M.; Frey, S.; Knoblauch, Vera; Wirz-Justice, A.

Evidence that the Lunar Cycle Influences Human Sleep

Current Biology, 23 (15), pp. 1-4, 2013.

(Abstract | PDF & Links | BibTeX)

Gabel, V.; Maire, M.; Chellappa, C.F. Reichert S.L.; Schmidt, C.; Hommes, V.; Viola, A.U.; Cajochen, C.

Effects of Artificial Dawn and Morning Blue Light on Daytime Cognitive Performance, Well-being, Cortisol and Melatonin Levels

Chronobiology International, 30, pp. 988-97, 2013.

(Abstract | PDF & Links | BibTeX)

Cajochen, C.

Chronobiologie: Licht- und Wachtherapie bei psychiatrischen Erkrankungen

PSYCH up2date, 7 (3), pp. 173-184, 2013.

(Abstract | PDF & Links | BibTeX)

Chellappa, S.L.; Steiner, R.; Oelhafen, P.; Lang, D.; Götz, T.; Krebs, J.; Cajochen, C.

Acute exposure to evening blue-enriched light impacts on human sleep

Journal of Sleep Research, 2013.

(Abstract | PDF & Links | BibTeX)

Chellappa, S.L.; Cajochen, C.

Ultradian and circadian modulation of dream recall: EEG correlates and age effects

International Journal of Psychophysiology, 89, pp. 165–170, 2013.

(Abstract | PDF & Links | BibTeX)

Bromundt, V.; Wirz-Justice, A.; Kyburz, S.; Opwis, K.; Dammann, G.; Cajochen, C.

Circadian sleep-wake cycles, well-being, and light therapy in Borderline Personality Disorder

Journal of Personality Disorders, 26. doi: 10.1521/pedi_2012_26_057, 2012.

(PDF & Links | BibTeX)

Kolodyazhniy, V.; Späti, J.; Frey, S.; Götz, T.; Wirz-Justice, A.; Kräuchi, K.; Cajochen, C.; Wilhelm, F.H.

An improved method for estimating human circadian phase derived from multichannel ambulatory monitoring and artificial neural networks

Chronobiology International Aug. 14. doi:10.3109/07420528.2012.700669, 2012.

(PDF & Links | BibTeX)

Schmidt, C.; Peigneux, P.; Cajochen, C.

Age-related changes in sleep and circadian rhythms: impact on cognitive performance and underlying neuroanatomical networks

Frontiers in Neurology 3:118. doi: 10.3389/fneur.2012.00118, 2012.

(PDF & Links | BibTeX)

Frey, S.; Birchler-Pedross, A.; Hofstetter, M.; Brunner, P.; Götz, T.; Münch, M.; Blatter, K.; Knoblauch, V.; Wirz-Justice, A.; Cajochen, C.

Challenging the sleep homeostat: Sleep in depression is not premature aging

Sleep Medicine 13: 933-945, 2012.

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Frey, S.; Birchler-Pedross, A.; Hofstetter, M.; Brunner, P.; Götz, T.; Münch, M.; Blatter, K.; Knoblauch, V.; Wirz-Justice, A.; Cajochen, C.

Young women with major depression live on higher homeostatic sleep pressure than healthy controls

Chronobiology International 29(3): 278-294, 2012.

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Dallmann, R.; Viola, A.U.; Tarokha, L.; Cajochen, C.; Brown, S.A.

The human circadian metabolome

PNAS January 31 doi: 10.1073/pnas.1114410109 (Epub ahead of print), 2012.

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Schmidt, C.; Peigneux, P.; Leclercq, Y.; Sterpenich, V.; Vandewalle, G.; Phillips, C.; Berthomier, P.; Berthomier, C.; Tinguely, G.; Gais, S.; Schabus, M.; Desseilles, M.; Dang-Vu, T.; Salmon, E.; Degueldre, C.; Balteau, E.; Luxen, A.; Cajochen, C.; Maquet, P.; Collette, F.

Circadian preference modulates the neural substrate of conflict processing across the day

PLoS ONE 7(1): e29658, 2012.

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Chellappa, S.L.; Münch, M.; Knoblauch, V.; Cajochen, C.

Age effects on spectral electroencephalogram activity prior to dream recall

J Sleep Res. Aug 18. doi: 10.1111/j.1365-2869.2011.00947.x (Epub ahead of print), 2011.

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Viola, A.U.; Chellappa, S.L.; Archer, S.N.; Pugin, F.; Götz, T.; Dijk, D.J.; Cajochen, C.

Interindividual differences in circadian rhythmicity and sleep homeostasis in older people: effect of a PER3 polymorphism

Neurobiology of Aging Dec 12 (Epub ahead of print), 2011.

(PDF & Links | BibTeX)

Chellappa, S.L.; Viola, A.U.; Schmidt, C.; Bachmann, V.; Gabel, V.; Maire, M.; Reichert, C.F.; Valomon, A.; Götz, T.; Landolt, H.P.; Cajochen, C.

Human melatonin and alerting response to blue-enriched light depend on a polymorphism in the clock gene PER3

J Clin Endocrinol Metab 97(3), 2011.

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Birchler-Pedross, A.; Frey, S.; Chellappa, S.L.; Götz, T.; Brunner, P.; Knoblauch, V.; Wirz-Justice, A.; Cajochen, C.

Higher frontal EEG synchronization in young women with major depression: A marker for increased homeostatic sleep pressure?

Sleep 34(12): 1699-1706, 2011.

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Chellappa, S.L.; Gordijn, M.C.M.; Cajochen, C.

Can light make us bright? Effects of light on cognition sleep

In: Kerkhof G. and Van Dongen H.P.A. (Eds), Progress in Brain Research 190: 119-133, 2011.

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Wirz-Justice, A.; Cajochen, C.

Zirkadiane Rhythmen und Depression: chronobiologische Behandlungsmöglichkeiten

Schweiz Med Forum 11(32-33): 536-541, 2011.

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Pagani, L.; Schmit, t K.; Meier, F.; Izakovic, J.; Roemer, K.; Viola, A.U.; Cajochen, C.; Wirz-Justice, A.; Brown, S.A.; Eckert, A.

Serum factors in older individuals change cellular clock properties

PNAS 108(17): 7218-7223, 2011.

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Chellappa, S.L.; Frey, S.; Knoblauch, V.; Cajochen, C.

Cortical activation patterns herald successful dream recall after NREM and REM sleep

Biol Psychology 87: 251-256, 2011.

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Bromundt, V.; Köster, M.; Georgiev-Kill, A.; Opwis, K.; Wirz-Justice, A.; Stoppe, G.; Cajochen, C.

Sleep-wake cycles and cognitive functioning in schizophrenia.

Br J Psychiatry, epub 10.1192/bjp.bp.110.078022, 2011.

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Cajochen, C.; Frey, S.; Anders, D.; Späti, J.; Bues, M.; Pross, A.; Mager, R.; Wirz-Justice, A.; Stefani, O.

Evening exposure to a light emitting diodes (LED)-backlit computer screen affects circadian physiology and cognitive performance

2011.

(PDF & Links | BibTeX)

Chellappa, S.L.; Steiner, R.; Blattner, P.; Oelhafen, P.; Götz, T.; Cajochen, C.

Non-Visual Effects of Light on Melatonin, Alertness and Cognitive Performance: Can Blue-Enriched Light Keep Us Alert?

PLoS ONE 6(1): e16429. doi:10.1371/journal.pone.0016429, 2011.

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Kolodyazhniy, V.; Späti, J.; Frey, S.; Götz, T.; Wirz-Justice, A.; Kräuchi, K.; Cajochen, C.; Wilhelm, F.H.

Estimation of human circadian phase via a multi-channel ambulatory monitoring system and a multiple regression model.

J Biol Rhythms 26: 55-67., 2011.

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Brown, S.A.; Pagani, L.; Cajochen, C.; Eckert, A.

Systemic and Cellular Reflections on ageing and the circadian oscillator - A Mini-Review.

Gerontology. Oct 28., 2010.

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Cajochen, C.; Chellappa, S.L.; Schmidt, C.

What keeps us awake?--the role of clocks and hourglasses, light, and melatonin.

Int Rev Neurobiol 93:57-90., 2010.

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Jung, C.M.; Khalsa, S.B.; Scheer, F.A.; Cajochen, C.; Lockley, S.W.; Czeisler, C.A.; Wright, K.P. Jr.

Acute effects of bright light exposure on cortisol levels.

J Biol Rhythms. 25(3):208-16., 2010.

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Pagani, L.; Semenova, E.A.; Moriggi, E.; Revell, V.L.; Hack, L.M.; Lockley, S.W.; Arendt, J.; Skene, D.J.; Meier, F.; Izakovic, J.; Wirz-Justice, A.; Cajochen, C.; Sergeeva, O.J.; Cheresiz, S.V.; Danilenko, K.V.; Eckert, A.; Brown, S.A.

The physiological period length of the human circadian clock in vivo is directly proportional to period in human fibroblasts.

PLoS One. 15;5(10):e13376., 2010.

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Wirz-Justice, A.; Schröder, C.M.; Gasio, P. Fontana; Cajochen, C.; Savaskan, E.

The circadian rest-activity cycle in Korsakoff psychosis.

Am J Geriatr Psychiatry 18(1): 33-41., 2010.

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Pagani, L.; Semenova, E.A.; Moriggi, E.; Revell, V.L.; Hack, L.M.; Lockley, S.W.; Arendt, J.; Skene, D.J.; Meier, F.; Izakovic, J.; Wirz-Justice, A.; Cajochen, C.; Sergeeva, O.J.; Cheresiz, S.V.; Danilenko, K.V.; Eckert, A.; Brown, S.A.

The physiological period length of the human circadian clock in vivo is directly proportional to period in human fibroblasts.

PLoS One. 15;5(10):e13376., 2010.

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Wirz-Justice, A.; Bromundt, V.; Cajochen, C.

Circadian disruption and psychiatric disorders: The importance of entrainment.

Sleep Med Clin, 4: 273-284., 2009.

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Birchler-Pedross, A.; Schröder, C.M.; Münch, M.; Knoblauch, V.; Blatter, K.; Schnitzler-Sack, C.; Wirz-Justice, A.; Cajochen, C.

Subjective well-being is modulated by circadian phase, sleep pressure, age, and gender.

Journal of Biological Rhythms, 24(3): 232-242., 2009.

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Chellappa, S.L.; Münch, M.; Blatter, K.; Knoblauch, V.; Cajochen, C.

Does the circadian modulation of dream recall modify with age?

Sleep, 32(9): 1201-1209., 2009.

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Chellappa, S.L.; Schröder, C.; Cajochen, C.

Chronobiology, excessive daytime sleepiness and depression: Is there a link?

Sleep Medicine, 10(5): 505-514., 2009.

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Frey, S.; Balu, S.; Greusing, S.; Rothen, N.; Cajochen, C.

Consequences of the timing of menarche on female adolescent sleep phase preference.

PLoS ONE, 4(4)., 2009.

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Jud, C.; Chappuis, S.; Revell, V.L.; Sletten, T.L.; Saaltink, D.-J.; Cajochen, C.; Skene, D.J.; Albrecht, U.

Age-dependent alterations in human PER2 levels after early morning blue light exposure.

Chronobiology International, 26(7): 1462-1469., 2009.

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Rosenberg, J.; Pusch, K.; Dietrich, R.; Cajochen, C.

The Tick-Tock of Language: Is Language Processing Sensitive to Circadian Rhythmicity and Elevated Sleep Pressure?

Chronobiology International, 26(5): 1-18., 2009.

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Schmidt, C.; Collette, F.; Leclercq, Y.; Sterpenich, V.; Vandewalle, G.; Berthomier, P.; Berthomier, C.; Phillips, C.; Tinguely, G.; Darsaud, A.; Gais, S.; Schabus, M.; Desseilles, M.; Dang-Vu, T.T.; Salmon, E.; Balteau, E.; Dequeldre, C.; Luxen, A.; Maquet, P.; Cajochen, C.; Peigneux, P.

Homeostatic sleep pressure and responses to sustained attention in the suprachiasmatic area.

Science, 324(5926):516-519., 2009.

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Späti, J.; Münch, M.; Blatter, K.; Knoblauch, V.; Jones, L.A.; Cajochen, C.

Impact of age, sleep pressure and circadian phase on time-of-day estimates.

Behav Brain Res, 201(1):48-52., 2009.

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Cajochen, C.; Biase, R. Di; Imai, M.

Interhemispheric EEG asymmetries during unilateral bright-light exposure

Am J Physiol Regulatory Integrative Comp Physiol, 294, pp. 1053-1060, 2008.

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Blatter, K.; Cajochen, C.

Circadian rhythms in cognitive performance: Methodological constraints, protocols, theoretical underpinnings.

Physiology & Behavior, 90: 196-208., 2007.

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Cajochen, C.

Alerting effects of light.

Sleep Med Rev, 11: 453-464., 2007.

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Münch, M.; Knoblauch, V.; Blatter, K.; Wirz-Justice, A.; Cajochen, C.

Is homeostatic sleep regulation under low sleep pressure modified by age?

Sleep, 30(6): 781-792., 2007.

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Schmidt, C.; Collette, F.; Cajochen, C.; Peigneux, P.

A time to think: circadian rhythms in human cognition.

Cogn Neuropsychol., 24(7):755-789., 2007.

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Cajochen, C.; Münch, M.; Knoblauch, V.; Blatter, K.; Wirz-Justice, A.

Age-related changes in the circadian and homeostatic regulation of human sleep.

Chronobiology International, 23: 461-474., 2006.

(PDF & Links | BibTeX)

Kräuchi, K.; Knoblauch, V.; Wirz-Justice, A.; Cajochen, C.

Challenging the sleep homeostat does not influence the thermoregulatory system in men: evidence from a nap vs. sleep-deprivation study.

American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, 290: R1052-R1061., 2006.

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Blatter, K.; Graw, P.; Münch, M.; Knoblauch, V.; Wirz-Justice, A.; Cajochen, C.

Gender and age differences in psychomotor vigilance under differential sleep pressure conditions.

Behavioural Brain Research, 168: 312-317., 2006.

(PDF & Links | BibTeX)

Cajochen, C.; Jud, C.; Münch, M.; Kobialka, S.; Wirz-Justice, A.; Albrecht, U.

Evening exposure to blue light stimulates the expression of the clock gene PER2 in humans

European Journal of Neuroscience, 23: 1082-1086., 2006.

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Kräuchi, K.; Cajochen, C.; Pache, M.; Flammer, J.; Wirz-Justice, A.

Thermoregulatory effects of melatonin in relation to sleepiness.

Chronobiology International, 23: 475-484., 2006.

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Münch, M.; Kobialka, S.; Steiner, R.; Oelhafen, P.; Wirz-Justice, A.; Cajochen, C.

Wavelength-dependent effects of evening light exposure on sleep architecture and sleep EEG power density in men.

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 290 : R1421-R1428., 2006.

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Savaskan, E.; Schnitzler, C.; Schröder, C.; Cajochen, C.; Müller-Spahn, F.; Wirz-Justice, A.

Treatment of behavioural, cognitive and circadian rest-activity cycle disturbances in Alzheimer's disease: haloperidol vs. quetiapine.

International Journal of Neuropsychopharmacology, 9: 507-516., 2006.

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Schmidt, C.; Peigneux, P.; Muto, V.; Schenkel, M.; Knoblauch, V.; Münch, M.; Quervain, D. J.-F. de; Wirz-Justice, A.; Cajochen, C.

Encoding difficulty promotes postlearning changes in sleep spindle activity during napping.

Journal of Neuroscience, 26(35): 8976-8982., 2006.

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Blatter, K.; Opwis, K.; Münch, M.; Wirz-Justice, A.; Cajochen, C.

Sleep loss-related decrements in planning performance in healthy elderly depend on task difficulty.

Journal of Sleep Research, 14: 409-417., 2005.

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Cajochen, C.

Schlafstörungen bei Schichtarbeit und Jetlag und die Rolle der inneren Uhr.

Praxis, 94: 1479-1483., 2005.

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Cajochen, C.

TAK-375 Takeda.

Current Opinion in Investigational Drugs, 6: 114-121., 2005.

(BibTeX)

Cajochen, C.; Münch, M.; Kobialka, S.; Kräuchi, K.; Steiner, R.; Oelhafen, P.; Orgül, S.; Wirz-Justice, A.

High sensitivity of human melatonin, alertness, thermoregulation and heart rate to short wavelength light.

Journal of Clinical Endocrinology and Metabolism, 90: 1311-1316., 2005.

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Knoblauch, V.; Münch, M.; Blatter, K.; Martens, W.L.J.; Schröder, C.; Schnitzler, C.; Wirz-Justice, A.; Cajochen, C.

Age-Related Changes in the Circadian Modulation of Sleep-Spindle Frequency During Nap Sleep.

Sleep, 28: 1093-1101, 2005.

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Kräuchi, K.; Cajochen, C.; Wirz-Justice, A.

Thermophysiologic aspects of the three-process-model of sleepiness regulation.

Clinics in Sports Medicine, 24: 287-300., 2005.

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Münch, M.; Cajochen, C.; Wirz-Justice, A.

Schlaf und zirkadiane Rhythmik im Alter.

Zeitschrift für Gerontologie und Geriatrie, 38 (Supplement 1) I/21–I/23., 2005.

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Münch, M.; Knoblauch, V.; Blatter, K.; Schröder, C.; Schnitzler, C.; Kräuchi, K.; Wirz-Justice, A.; Cajochen, C.

Age-related attenuation of the evening circadian arousal signal in humans.

Neurobiology of Aging, 26: 1307-1319, 2005.

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Cajochen, C.; Blatter, K.; Wallach, D.

Circadian and sleep-wake dependent impact on neurobehavioral function.

Psychologica Belgica, 44: 59-80., 2004.

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Cajochen, C.; Knoblauch, V.; Wirz-Justice, A.; Kräuchi, K.; Graw, P.; Wallach, D.

Circadian modulation of sequence learning under high and low sleep pressure conditions.

Behavioural Brain Research, 151: 167-176., 2004.

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Graw, P.; Kräuchi, K.; Knoblauch, V.; Renz, C.; Wirz-Justice, A.; Cajochen, C.

Circadian and wake-dependent modulation of fastest and slowest reaction times of the Psychomotor Vigilance Task (PVT).

Physiology & Behavior, 80: 695-701., 2004.

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Kräuchi, K.; Cajochen, C.; Wirz-Justice, A.

Waking up properly: is there a role of thermoregulation in sleep inertia?

Journal of Sleep Research, 13: 121-127., 2004.

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Münch, M.; Knoblauch, V.; Blatter, K.; Schröder, C.; Schnitzler, C.; Kräuchi, K.; Wirz-Justice, A.; Cajochen, C.

The frontal predominance in human EEG delta activity after sleep loss decreases with age.

European Journal of Neuroscience, 20: 1402-10., 2004.

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Wirz-Justice, A.; Kräuchi, K.; Cajochen, C.; Danilenko, K.V.; Renz, C.; Weber, J.

Evening melatonin and bright light administration induce additive phase shifts in dim light melatonin onset.

Journal of Pineal Research, 36: 192-194., 2004.

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Wyatt, J.K.; Cajochen, C.; Cecco, A. Ritz-De; Czeisler, C.A.; Dijk, D.J.

Low-dose repeated caffeine administration for circadian-phase-dependent performance degradation during extended wakefulness.

Sleep, 27: 374-381., 2004.

(BibTeX)

Cajochen, C.; Dijk, D.J.

Electroencephalographic activity during wakefulness, rapid eye movement, and non-rapid- eye movement sleep in humans: comparison of their circadian and homeostatic modulation.

Sleep and Biological Rhythms, 2: 85-95., 2003.

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Cajochen, C.; Jewett, M.E.; Dijk, D.J.

Human circadian melatonin rhythm phase delay during a fixed sleep-wake schedule interspersed with nights of sleep deprivation.

Journal of Pineal Research, 35: 149-157., 2003.

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Cajochen, C.; Kräuchi, K.; Wirz-Justice, A.

Role of melatonin in the regulation of human circadian rhythms and sleep.

Journal of Neuroendocrinology, 15: 432-437., 2003.

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Danilenko, K.V.; Cajochen, C.; Wirz-Justice, A.

Is sleep per se a zeitgeber in humans?

Journal of Biological Rhythms, 18: 170-178., 2003.

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Gasio, P. Fontana; Kräuchi, K.; Cajochen, C.; Someren, E.J.W. van; Amrhein, I.; Pache, M.; Savaskan, E.; Wirz-Justice, A.

Dawn-dusk simulation light therapy of disturbed circadian rest-activity cycles in demented elderly.

Experimental Gerontology, 38: 207-216., 2003.

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Khalsa, S.B.; Jewett, M.E.; Cajochen, C.; Czeisler, C.A.

A phase-response curve to single bright light pulses in human subjects.

Journal of Physiology, 549: 945-52., 2003.

(BibTeX)

Knoblauch, V.; Martens, W.J.L.; Wirz-Justice, A.; Cajochen, C.

Human sleep spindle characteristics after sleep deprivation.

Clinical Neurophysiology, 114: 2258-2267., 2003.

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Knoblauch, V.; Martens, W.J.L.; Wirz-Justice, A.; Kräuchi, K.; Cajochen, C.

Regional differences in the circadian modulation of human sleep spindle characteristics.

European Journal of Neuroscience, 18: 155-163., 2003.

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Knoblauch, V.; Kräuchi, K.; Renz, C.; Wirz-Justice, A.; Cajochen, C.

Homeostatic control of slow wave- and spindle frequency activity during human sleep: effect of differential sleep pressure and brain topography.

Cerebral Cortex, 12: 1092-1100., 2002.

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Kräuchi, K.; Cajochen, C.; Werth, E.; Wirz-Justice, A.

Alteration of internal circadian phase relationships after timed CHO-rich meals in humans.

Journal of Biological Rhythms, 17: 364-376., 2002.

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Cajochen, C.; Wyatt, J. K.; Czeisler, C.A.; Dijk, D.J.

Separation of circadian and wake-duration dependent modulation of EEG activation during wakefulness.

Neuroscience, 114: 1047-60., 2002.

(BibTeX)

Cajochen, C.; Knoblauch, V.; Kräuchi, K.; Renz, C.; Wirz-Justice, A.

Dynamics of frontal EEG activity, sleepiness and body temperature under high and low sleep pressure.

Neuroreport 12: 2277-2281., 2001.

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Graw, P.; Werth, E.; Kräuchi, K.; Gutzwiller, F.; Cajochen, C.; Wirz-Justice, A.

Early morning melatonin administration impairs psychomotor vigilance.

Behavioural Brain Research, 121: 167-172., 2001.

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Pache, M.; Kräuchi, K.; Cajochen, C.; Wirz-Justice, A.; Dubler, B.; Flammer, J.; Kaiser, H.J.

Cold feet and prolonged sleep-onset latency in vasospastic syndrome.

The Lancet, 358: 125-126., 2001.

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Wirz-Justice, A.; Haug, H.J.; Cajochen, C.

Disturbed circadian rest-activity cycles in schizophrenia patients: an effect of drugs?

Schizophr. Bull. 27: 497-502, 2001.

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Cajochen, C.; Brunner, D.P.; Kräuchi, K.; Graw, P.; Wirz-Justice, A

EEG and subjective sleepiness during extended wakefulness in Seasonal Affective Disorder: circadian and homeostatic influences.

Biological Psychiatry, 47: 610-617., 2000.

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Cajochen, C.; Zeitzer, J. M.; Czeisler, C.A.; Dijk, D.J.

Dose-response relationship for light intensity and ocular and electroencephalo-graphic correlates of human alertness.

Behavioural Brain Research 115: 75 - 83, 2000.

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Danilenko, K.V.; Wirz-Justice, A.; Kräuchi, K.; Cajochen, C.; Weber, J.M.; Fairhurst, S.; Terman, M.

Phase advance after one or three simulated dawns in humans.

Chronobiology International, 17: 659-668., 2000.

(BibTeX)

Kräuchi, K.; Cajochen, C.; Werth, E.; Wirz-Justice, A.

A functional link between distal vasodilation and sleep onset latency?

American Journal of Physiology, 278: R741-R748., 2000.

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Wirz-Justice, A.; Quinto, C.; Cajochen, C.; Werth, E.; Hock, C.

A rapid-cycling bipolar patient treated with long nights, bedrest, and light.

Biological Psychiatry, 45: 1075-1077., 1999.

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Kräuchi, K.; Cajochen, C.; Werth, E.; Wirz-Justice, A.

Warm feet promote the rapid onset of sleep.

Nature, 401: 36-37., 1999.

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Kräuchi, K.; Cajochen, C.; Wirz-Justice, A.

Circadian and homeostatic regulation of core body temperature and alertness in humans: what is the role of melatonin?

K.-I. Honma and S. Honma (Eds.), Circadian Clocks and Entrainment, Hokkaido University Press, Sapporo, 7: 131-146., 1998.

(BibTeX)

Cajochen, C.; Kräuchi, K.; Danilenko, K.V.; Wirz-Justice, A.

Evening administration of melatonin and bright light: interactions on the EEG during sleep and wakefulness.

Journal of Sleep Research, 7: 145-157., 1998.

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Kräuchi, K.; Cajochen, C.; Möri, D.; Graw, P.; Wirz-Justice, A.

Melatonin and S-20098 advance circadian phase and nocturnal regulation of core body temperature.

American Journal of Physiology, 272: R1178-R1188., 1997.

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Kräuchi, K.; Cajochen, C.; Wirz-Justice, A.

A relationship between heat loss and sleepiness: effects of postural change and melatonin administration.

Journal of Applied Physiology, 83: 134-139., 1997.

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Wirz-Justice, A.; Cajochen, C.; Nussbaum, P.

A schizophrenic patient with an arrhythmic circadian rest-activity cycle.

Psychiatry Research, 73: 83-90., 1997.

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Dijk, D.-J.; Cajochen, C.

Melatonin and the circadian regulation of sleep initiation, consolidation, structure and the sleep EEG.

Journal of Biological Rhythms, 12: 627-635., 1997.

(BibTeX)

Cajochen, C.; Kräuchi, K.; Möri, D.; Graw, P.; Wirz-Justice, A.

Melatonin and S-20098 phase advance REM sleep propensity and the wake-up threshold without modifying NREM-sleep homeostasis.

American Journal of Physiology, 272: R1189-R1196., 1997.

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Cajochen, C.; Kräuchi, K.; Wirz-Justice, A.

The acute soporific action of daytime melatonin administration: effects on waking EEG power density and alertness.

Journal of Biological Rhythms, 12: 636- 643., 1997.

(BibTeX)