@article{nokey,

title = {Afternoon to early evening bright light exposure reduces later melatonin production in adolescents},

author = {R. Lazar and F. Fazlali and M. Dourte and C. Epple and O. Stefani and M. Spitschan and C. Cajochen},

url = {https://doi.org/10.1038/s44323-025-00040-6},

doi = {10.1038/s44323-025-00040-6},

year  = {2025},

date = {2025-06-30},

urldate = {2025-06-30},

journal = {npj Biol Timing Sleep},

volume = {2},

number = {25},

abstract = {Whether light exposure during the day reduces non-visual light effects later in the evening has not been studied in adolescents. We investigate whether afternoon-early evening (AEE) light interventions (130 lx, 2500 lx, 4.5 h, compared to 6.5 lx illuminance) would increase melatonin levels during later evening light exposure (130 lx) in a counterbalanced crossover study with 22 adolescents (14-17 years, 11 female). Contrary to our hypothesis, evening melatonin levels decreased after AEE bright light exposure, while sleepiness and vigilance were unaffected, and skin temperature showed no clear changes. The AEE light had acute alerting effects and bright light exposure in the 32 h before laboratory entry was associated with higher evening melatonin and sleepiness. These findings suggest that bright AEE light increases alertness but may delay melatonin production by interfering with circadian rhythms. The study highlights the complex effects of light timing and its implications for managing adolescents’ light exposure.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {No association between chronotype and cardiovascular response to a cognitive challenge in the morning using a Bayesian approach},

author = {L. N. Wüst and C. Cajochen and R Lasauskaite},

url = {https://www.sciencedirect.com/science/article/pii/S2451994425000148},

doi = {10.1016/j.nbscr.2025.100125},

year  = {2025},

date = {2025-05-01},

urldate = {2025-05-01},

journal = {Neurobiology of Sleep and Circadian Rhythms},

pages = {100125},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Non-image-forming effects of daytime electric light exposure in humans: A systematic review and meta-analyses of physiological, cognitive, and subjective outcomes},

author = {R Lasauskaite and L. N. Wüst and I. Schöllhorn and M Richter and C. Cajochen},

url = {https://www.tandfonline.com/doi/full/10.1080/15502724.2025.2493669},

doi = {10.1080/15502724.2025.2493669},

year  = {2025},

date = {2025-04-14},

urldate = {2025-04-14},

journal = {LEUKOS},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wüst2024b,

title = {Effects of sleep restriction and light intensity on mental effort during cognitive challenge},

author = {L. N. Wüst and R Lasauskaite},

url = {https://www.sciencedirect.com/science/article/abs/pii/S016787602400165X},

doi = {10.1016/j.ijpsycho.2024.112461},

year  = {2024},

date = {2024-10-31},

urldate = {2024-10-31},

journal = {International Journal of Psychophysiology},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = { Effects of caffeine intake on pupillary parameters in humans: a systematic review and meta-analysis. },

author = {EV Hartmann and CF Reichert and M Spitschan},

doi = { Behav Brain Funct. 2024 Aug 5;20(1):19. },

year  = {2024},

date = {2024-08-05},

urldate = {2024-08-05},

journal = {Behav Brain Funct.},

volume = {20},

number = {19},

issue = {1},

pages = {1-12},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Towards an evidence-based integrative lighting score: a proposed multi-level approach },

author = {O. Stefani and I. Schöllhorn and M. Münch},

doi = {https://doi.org/10.1080/07853890.2024.2381220},

year  = {2024},

date = {2024-07-25},

journal = {Annales of Medicine},

volume = {56},

issue = {1},

pages = {1-16},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{M2024,

title = {Sleep and sleep disorders during pregnancy and postpartum: The Life-ON study. },

author = {M. Manconi and LC. van der Gaag and F. Mangili and C. Garbazza and S. Riccardi and C. Cajochen and S. Mondini and F. Furia and E. Zambrelli and S. Baiardi and A. Giordano and N. Rizzo and C. Fonti and E. Viora and A. D'Agostino and A. Cicolin and F. Cirignotta and Life-ON study group},

doi = {oi: 10.1016/j.sleep.2023.10.021},

year  = {2024},

date = {2024-07-01},

urldate = {2024-07-01},

journal = {Sleep Medicine},

volume = {113},

pages = {41-48},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Inverse association between slow-wave sleep and low-grade inflammation in children and adolescents with major depressive disorder },

author = {MA. Strumberger and I. Häberling and S. Emery and M. Albermann and N. Baumgartner and C. Pedrett and S. Wild and B. Contin-Waldvogel and S. Walitza and G. Berger and K. Schmeck and C. Cajochen 

},

doi = {doi: 10.1016/j.sleep.2024.04.007},

year  = {2024},

date = {2024-07-01},

urldate = {2024-07-01},

journal = {Sleep Medicine},

volume = {119},

pages = {103-113},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Metadata recommendations for light logging and dosimetry datasets},

author = {M. Spitschan and G. Hammad and C. Blume and C. Schmidt and D.J. Skene and K. Wulff and N. Santhi and J. Zauner and M. Münch},

year  = {2024},

date = {2024-06-24},

urldate = {2024-06-24},

journal = {BMC Digital Health},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Repeated caffeine intake suppresses cerebral grey matter responses to chronic sleep restriction in an A1 adenosine receptor-dependent manner: a double-blind randomized controlled study with PET-MRI},

author = {Y.-S. Lin and D. Lange and D. Baur and A. Foerge and E.-M. Elmenhorst and B. Neumaier and A. Bauer and D. Aeschbach and H.-P. Landolt and D. Elmenhorst},

doi = {10.1038/s41598-024-61421-8},

year  = {2024},

date = {2024-06-03},

journal = {Scientific Reports},

volume = {14},

issue = {1},

pages = {12724},

abstract = {Evidence has shown that both sleep loss and daily caffeine intake can induce changes in grey matter (GM). Caffeine is frequently used to combat sleepiness and impaired performance caused by insufficient sleep. It is unclear (1) whether daily use of caffeine could prevent or exacerbate the GM alterations induced by 5-day sleep restriction (i.e. chronic sleep restriction, CSR), and (2) whether the potential impact on GM plasticity depends on individual differences in the availability of adenosine receptors, which are involved in mediating effects of caffeine on sleep and waking function. Thirty-six healthy adults participated in this double-blind, randomized, controlled study (age = 28.9 ± 5.2 y/; F:M = 15:21; habitual level of caffeine intake < 450 mg; 29 homozygous C/C allele carriers of rs5751876 of ADORA2A, an A2A adenosine receptor gene variant). Each participant underwent a 9-day laboratory visit consisting of one adaptation day, 2 baseline days (BL), 5-day sleep restriction (5 h time-in-bed), and a recovery day (REC) after an 8-h sleep opportunity. Nineteen participants received 300 mg caffeine in coffee through the 5 days of CSR (CAFF group), while 17 matched participants received decaffeinated coffee (DECAF group). We examined GM changes on the 2nd BL Day, 5th CSR Day, and REC Day using magnetic resonance imaging and voxel-based morphometry. Moreover, we used positron emission tomography with [18F]-CPFPX to quantify the baseline availability of A1 adenosine receptors (A1R) and its relation to the GM plasticity. The results from the voxel-wise multimodal whole-brain analysis on the Jacobian-modulated T1-weighted images controlled for variances of cerebral blood flow indicated a significant interaction effect between caffeine and CSR in four brain regions: (a) right temporal-occipital region, (b) right dorsomedial prefrontal cortex (DmPFC), (c) left dorsolateral prefrontal cortex (DLPFC), and (d) right thalamus. The post-hoc analyses on the signal intensity of these GM clusters indicated that, compared to BL, GM on the CSR day was increased in the DECAF group in all clusters but decreased in the thalamus, DmPFC, and DLPFC in the CAFF group. Furthermore, lower baseline subcortical A1R availability predicted a larger GM reduction in the CAFF group after CSR of all brain regions except for the thalamus. In conclusion, our data suggest an adaptive GM upregulation after 5-day CSR, while concomitant use of caffeine instead leads to a GM reduction. The lack of consistent association with individual A1R availability may suggest that CSR and caffeine affect thalamic GM plasticity predominantly by a different mechanism. Future studies on the role of adenosine A2A receptors in CSR-induced GM plasticity are warranted.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Effects of evening smartphone use on sleep and declarative memory consolidation in male adolescents and young adults},

author = {C. Höhn and MA. Hahn and G. Gruber and P. Pletzer and C. Cajochen and K. Hoedlmoser 

},

doi = {DOI: 10.1093/braincomms/fcae173},

year  = {2024},

date = {2024-05-17},

urldate = {2024-05-17},

journal = {Brain Commun Brain communications},

volume = {6},

issue = {3},

pages = {p.fcae173},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wüst2024a,

title = {Impact of one night of sleep restriction on sleepiness and cognitive function: A systematic review and meta-analysis},

author = {L. N. Wüst and N. C. Capdevila and L. T. Lane and C. F. Reichert and R Lasauskaite},

url = {https://www.sciencedirect.com/science/article/pii/S1087079224000443},

doi = {10.1016/j.smrv.2024.101940},

year  = {2024},

date = {2024-04-26},

urldate = {2024-04-26},

journal = {Sleep Medicine Reviews},

volume = {76},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Miller2024,

title = {ICNIRP Statement on Short Wavelength Light Exposure from Indoor Artificial Sources and Human Health},

author = {S. Miller and C. Cajochen and A.Green and J. Hanifin and A. Huss and K. Karipidis and S. Loughran and G. Oftedal and J. O'Hagan and D. H Sliney and R. Croft and E. van Rongen and N. Cridland and G. d'Inzeo and A. Hirata and C. Marino and M. Röösli and S.Watanabe },

doi = {10.1097/HP.0000000000001790},

year  = {2024},

date = {2024-04-01},

urldate = {2024-04-01},

journal = {Health Physics},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Aging effects on the encoding/retrieval flip in associative memory: fMRI evidence from incidental contingency learning },

author = {E. Schneider and M. Rajkovic and R. Krug and MP. Caviezel and CF. Reichert and O. Bieri and A. Schmidt and S. Borgwardt and T. Leyhe and T. Linnemann and AB. Brühl and UE. Lang and T. Melcher 

},

doi = { doi: 10.3389/fnagi.2024.1357695},

year  = {2024},

date = {2024-03-13},

urldate = {2024-03-13},

journal = { Front Aging Neurosci  },

volume = {16},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Regulation of pupil size in natural vision across the human lifespan},

author = {R. Lazar and J. Degen and A-S. Fiechter and A. Monticelli and M. Spitschan },

doi = {doi.org/10.1098/rsos.191613},

year  = {2024},

date = {2024-02-27},

urldate = {2024-02-27},

journal = {R. Soc. Open Sci},

volume = {11},

pages = {191613},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {The sleep-circadian interface: A window into mental disorders},

author = {N. Meyer and R. Lok and C. Schmidt and SD. Kyle and CA. McClung CA and C. Cajochen and FAJL. Scheer and MW. Jones and SL Chellappa},

doi = {doi: 10.1073/pnas.2214756121.},

year  = {2024},

date = {2024-02-23},

urldate = {2024-02-23},

journal = {Proc Natl Acad Sci U S A.},

volume = {121},

issue = {9},

pages = {e2214756121},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Ultradian sleep cycles: Frequency, duration, and associations with individual and environmental factors-A retrospective study },

author = {C. Cajochen and CF. Reichert and M. Münch and V. Gabel and O. Stefani and SL. Chellappa and C. Schmidt 

},

doi = {https://doi.org/10.1016/j.sleh.2023.09.002},

year  = {2024},

date = {2024-02-10},

urldate = {2024-02-10},

journal = {Sleep Health},

number = {1},

issue = {Supplement},

pages = {S52-S62},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Eating during the biological night is associated with nausea },

author = {K-M. Zitting and CM. Isherwood and RK. Yuan and W. Wang and N. Vujovic and M. Münch and SW. Cain and JS. Williams and OM. Buxton and CA. Czeisler and JF. Duffy 

},

doi = {10.1016/j.sleh.2023.08.004. },

year  = {2024},

date = {2024-02-10},

urldate = {2024-02-10},

journal = {Sleep Health},

issue = {1, Supplement},

pages = {S144-S148},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Circadian- and wake-dependent influences on face-name memory in healthy men and women over 3weeks of chronic sleep restriction },

author = {RK. Yuan and YA. Kim and SW. Cain and MY. Münch and JM. Ronda and W. Wang and CA. Czeisler and JF. Duffy 

},

doi = {doi: 10.1016/j.sleh.2023.08.011},

year  = {2024},

date = {2024-02-10},

urldate = {2024-07-10},

journal = {Sleep Health},

issue = {1, Supplement},

pages = {S84-S88},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{IsabelSchöllhorn2023,

title = {The Impact of Pupil Constriction on the Relationship Between Melanopic EDI and Melatonin Suppression in Young Adult Males},

author = {I. Schöllhorn and O. Stefani and R. J Luca and M. Spitschan, and C. Epple and C. Cajochen

},

doi = {10.1177/07487304241226466},

year  = {2024},

date = {2024-02-01},

urldate = {2024-02-01},

journal = {Journal of Biological Rhythms},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Examining the structure validity of the Pittsburgh Sleep Quality Index among female workers during New Zealand’s initial COVID-19 lockdown},

author = {M. Helles and R. Fletcher and M. Münch and R. Gibson},

doi = {doi.org/10.1007/s41105-023-00509-6},

year  = {2024},

date = {2024-01-22},

journal = {Sleep and Biological Rhythms},

volume = {22},

pages = {217-225},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Blume2023,

title = {Effects of calibrated blue–yellow changes in light on the human circadian clock},

author = {C. Blume and C. Cajochen and I. Schöllhorn and H. C. Slawik and M. Spitschan},

doi = {10.1038/s41562-023-01791-7},

year  = {2023},

date = {2023-12-22},

urldate = {2023-12-22},

journal = {Nature Human Behaviour},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{pmid38092767,

title = {An inventory of human light exposure behaviour},

author = {Mushfiqul Anwar Siraji and R. Lazar and Juliëtte van Duijnhoven and Luc J M Schlangen and Shamsul Haque and Vineetha Kalavally and Céline Vetter and Gena L Glickman and Karin C H J Smolders and Manuel Spitschan },

doi = {10.1038/s41598-023-48241-y},

issn = {2045-2322},

year  = {2023},

date = {2023-12-01},

urldate = {2023-12-01},

journal = {Sci Rep},

volume = {13},

number = {1},

pages = {22151},

abstract = {Light exposure is an essential driver of health and well-being, and individual behaviours during rest and activity modulate physiologically relevant aspects of light exposure. Further understanding the behaviours that influence individual photic exposure patterns may provide insight into the volitional contributions to the physiological effects of light and guide behavioural points of intervention. Here, we present a novel, self-reported and psychometrically validated inventory to capture light exposure-related behaviour, the Light Exposure Behaviour Assessment (LEBA). An expert panel prepared the initial 48-item pool spanning different light exposure-related behaviours. Responses, consisting of rating the frequency of engaging in the per-item behaviour on a five-point Likert-type scale, were collected in an online survey yielding responses from a geographically unconstrained sample (690 completed responses, 74 countries, 28 time zones). The exploratory factor analysis (EFA) on an initial subsample (n = 428) rendered a five-factor solution with 25 items (wearing blue light filters, spending time outdoors, using a phone and smartwatch in bed, using light before bedtime, using light in the morning and during daytime). In a confirmatory factor analysis (CFA) performed on an independent subset of participants (n = 262), we removed two additional items to attain the best fit for the five-factor solution (CFI = 0.95, TLI = 0.95, RMSEA = 0.06). The internal consistency reliability coefficient for the total instrument yielded McDonald's Omega = 0.68. Measurement model invariance analysis between native and non-native English speakers showed our model attained the highest level of invariance (residual invariance CFI = 0.95, TLI = 0.95, RMSEA = 0.05). Lastly, a short form of the LEBA (n = 18 items) was developed using Item Response Theory on the complete sample (n = 690). The psychometric properties of the LEBA indicate the usability for measuring light exposure-related behaviours. The instrument may offer a scalable solution to characterise behaviours that influence individual photic exposure patterns in remote samples. The LEBA inventory is available under the open-access CC-BY license. Instrument webpage: https://leba-instrument.org/ GitHub repository containing this manuscript: https://github.com/leba-instrument/leba-manuscript .},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Schöllhorn2023b,

title = {Seasonal Variation in the Responsiveness of the Melanopsin System to Evening Light: Why We Should Report Season When Collecting Data in Human Sleep and Circadian Studies},

author = {I. Schöllhorn and O. Stefani and C. Blume and C. Cajochen},

url = {https://www.mdpi.com/2624-5175/5/4/44},

doi = {https://doi.org/10.3390/clockssleep5040044},

year  = {2023},

date = {2023-11-01},

urldate = {2023-11-01},

journal = {Clocks & Sleep},

abstract = {Abstract

It is well known that variations in light exposure during the day affect light sensitivity in the evening. More daylight reduces sensitivity, and less daylight increases it. On average days, we spend less time outdoors in winter and receive far less light than in summer. Therefore, it could be relevant when collecting research data on the non-image forming (NIF) effects of light on circadian rhythms and sleep. In fact, studies conducted only in winter may result in more pronounced NIF effects than in summer. Here, we systematically collected information on the extent to which studies on the NIF effects of evening light include information on season and/or light history. We found that more studies were conducted in winter than in summer and that reporting when a study was conducted or measuring individual light history is not currently a standard in sleep and circadian research. In addition, we sought to evaluate seasonal variations in a previously published dataset of 72 participants investigating circadian and sleep effects of evening light exposure in a laboratory protocol where daytime light history was not controlled. In this study, we selectively modulated melanopic irradiance at four different light levels (<90 lx). Here, we aimed to retrospectively evaluate seasonal variations in the responsiveness of the melanopsin system by combining all data sets in an exploratory manner. Our analyses suggest that light sensitivity is indeed reduced in summer compared to winter. Thus, to increase the reproducibility of NIF effects on sleep and circadian measures, we recommend an assessment of the light history and encourage standardization of reporting guidelines on the seasonal distribution of measurements.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Schöllhorn2023,

title = {Melanopic irradiance defines the impact of evening display light on sleep latency, melatonin and alertness},

author = {I Schöllhorn and O Stefani and R Lucas and M Spitschan and H Slawik and C. Cajochen},

url = {https://www.nature.com/articles/s42003-023-04598-4

},

doi = {https://doi.org/10.1038/s42003-023-04598-4},

year  = {2023},

date = {2023-03-01},

urldate = {2023-03-01},

journal = {Communications Biology},

number = {228},

issue = {6},

abstract = {Evening light-emitting visual displays may disrupt sleep, suppress melatonin and increase alertness. Here, we control melanopic irradiance independent of display luminance and colour, in 72 healthy males 4 h before habitual bedtime and expose each of them to one of four luminance levels (i.e., dim light, smartphone, tablet or computer screen illuminance) at a low and a high melanopic irradiance setting. Low melanopic light shortens the time to fall asleep, attenuates evening melatonin suppression, reduces morning melatonin, advances evening melatonin onset and decreases alertness compared to high melanopic light. In addition, we observe dose-dependent increases in sleep latency, reductions in melatonin concentration and delays in melatonin onset as a function of melanopic irradiance—not so for subjective alertness. We identify melanopic irradiance as an appropriate parameter to mitigate the unwanted effects of screen use at night. Our results may help the many people who sit in front of screens in the evening or at night to fall asleep faster, feel sleepier, and have a more stable melatonin phase by spectrally tuning the visual display light without compromising the visual appearance.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{light_effort,

title = {Lighting color temperature impacts effort-related cardiovascular response to an auditory short-term memory task},

author = {R Lasauskaite and M Richter and C. Cajochen},

url = {https://www.sciencedirect.com/science/article/pii/S0272494423000245},

doi = {10.1016/j.jenvp.2023.101976},

year  = {2023},

date = {2023-02-15},

urldate = {2023-02-15},

journal = {Journal of Environmental Psychology},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {The Light-Dosimeter: A new device to help advance research on the non-visual responses to light},

author = {J.R. Stampfli and B. Schrader and C. di Battista and R. Häfliger and O. Schälli and G. Wichmann and C. Zumbühl and P. Blattner and C. Cajochen and R. Lazar and M. Spitschan},

url = {https://journals.sagepub.com/doi/full/10.1177/14771535221147140},

doi = {https://doi.org/10.1177/14771535221147140},

year  = {2023},

date = {2023-02-13},

urldate = {2023-02-13},

journal = {Lighting Research & Technology},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{pylight_preprint,

title = {Open-source Python routines for the analysis of personalized light exposure data},

author = {G Hammad and K Wulff and DJ Skene and M Münch and M Spitschan},

url = {https://osf.io/msk9n/},

doi = {doi.org/10.31219/osf.io/msk9n},

year  = {2023},

date = {2023-01-25},

journal = {OSF Preprints},

keywords = {},

pubstate = {forthcoming},

tppubtype = {article}

}

@article{nokey,

title = {Brain activity during a working memory task after daily caffeine intake and caffeine withdrawal: a  randomized double-blind placebo-controlled trial.},

author = {Y.-S. Lin and J. Weibel and H.-P. Landolt and F. Santini and H. Slawik and S. Borgwardt and C. Cajochen and C. F. Reichert},

doi = {10.1038/s41598-022- 26808-5},

year  = {2023},

date = {2023-01-18},

urldate = {2023-01-18},

journal = {Scientific Reports},

volume = {13},

number = {1002},

issue = {1},

abstract = {Acute caffeine intake has been found to increase working memory (WM)-related brain activity in healthy adults without improving behavioral performances. The impact of daily caffeine intake-a ritual shared by 80% of the population worldwide-and of its discontinuation on working memory and its neural correlates remained unknown. In this double-blind, randomized, crossover study, we examined working memory functions in 20 young healthy non-smokers (age: 26.4 ± 4.0 years; body mass index: 22.7 ± 1.4 kg/m2; and habitual caffeine intake: 474.1 ± 107.5 mg/day) in a 10-day caffeine (150 mg × 3 times/day), a 10-day placebo (3 times/day), and a withdrawal condition (9-day caffeine followed by 1-day placebo). Throughout the 10th day of each condition, participants performed four times a working memory task (N-Back, comprising 3- and 0-back), and task-related blood-oxygen-level-dependent (BOLD) activity was measured in the last session with functional magnetic resonance imaging. Compared to placebo, participants showed a higher error rate and a longer reaction time in 3- against 0-back trials in the caffeine condition; also, in the withdrawal condition we observed a higher error rate compared to placebo. However, task-related BOLD activity, i.e., an increased attention network and decreased default mode network activity in 3- versus 0-back, did not show significant differences among three conditions. Interestingly, irrespective of 3- or 0-back, BOLD activity was reduced in the right hippocampus in the caffeine condition compared to placebo. Adding to the earlier evidence showing increasing cerebral metabolic demands for WM function after acute caffeine intake, our data suggest that such demands might be impeded over daily intake and therefore result in a worse performance. Finally, the reduced hippocampal activity may reflect caffeine-associated hippocampal grey matter plasticity reported in the previous analysis. The findings of this study reveal an adapted neurocognitive response to daily caffeine exposure and highlight the importance of classifying impacts of caffeine on clinical and healthy populations.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Danilenko2022,

title = {Wearable Light-and-Motion Dataloggers for Sleep/Wake Research: A Review},

author = {K. Danilenko and O. Stefani and K. Voronin and M. Mezhakova and I. Petrov and M. Borisenkov and A. Markov and D. Gubin },

editor = {Sung Bum Pan},

url = {https://www.mdpi.com/2076-3417/12/22/11794/htm},

doi = {https://doi.org/10.3390/app122211794},

issn = {2076-3417},

year  = {2022},

date = {2022-11-20},

journal = {Applied Sciences},

volume = {12},

number = {22},

abstract = {Long-term recording of a person’s activity (actimetry or actigraphy) using devices typically worn on the wrist is increasingly applied in sleep/wake, chronobiological, and clinical research to estimate parameters of sleep and sleep-wake cycles. With the recognition of the importance of light in influencing these parameters and with the development of technological capabilities, light sensors have been introduced into devices to correlate physiological and environmental changes. Over the past two decades, many such new devices have appeared from different manufacturers. One of the aims of this review is to help researchers and clinicians choose the data logger that best fits their research goals. Seventeen currently available light-and-motion recorders entered the analysis. They were reviewed for appearance, dimensions, weight, mounting, battery, sensors, features, communication interface, and software. We found that all devices differed from each other in several features. In particular, six devices are equipped with a light sensor that can measure blue light. It is noteworthy that blue light most profoundly influences the physiology and behavior of mammals. As the wearables market is growing rapidly, this review helps guide future developments and needs to be updated every few years.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Weng2022,

title = {Impact of Evening Light Exposures with Different Solid Angles on Circadian Melatonin Rhythms, Alertness, and Visual Comfort in an Automotive Setting},

author = {M. Weng and I. Schöllhorn and M. Kazhura and B. Cardini and O. Stefani},

editor = {Robert Lucas},

url = {https://www.mdpi.com/2624-5175/4/4/47},

doi = { https://doi.org/10.3390/clockssleep4040047},

issn = {2624-5175},

year  = {2022},

date = {2022-10-26},

journal = {Clocks & Sleep},

volume = {4},

number = {4},

pages = {607-622},

abstract = {Future automotive interior lighting might have the potential to go beyond decorative purposes by influencing alertness, circadian physiology, and sleep. As the available space in the interior of an automobile for lighting applications is limited, understanding the impact of various luminous surface sizes on non-image-forming effects is fundamental in this field. In a laboratory study using a within-subject design, 18 participants were exposed to two bright light conditions with different solid angles and one dim light condition in a balanced, randomized order during the course of the evening. Our results demonstrate that both light conditions significantly increased subjective alertness and reduced salivary melatonin concentration but not cognitive performance compared to dim light. The solid angle of light exposure at constant corneal illuminance only affected visual comfort. While subjective alertness can be increased and melatonin can be attenuated with rather small luminaires, larger solid angles should be considered if visual comfort is a priority.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{BrBehImmHe,

title = {Preliminary evidence that daily light exposure enhances the antibody response to influenza vaccination in patients with dementia},

author = {M. Münch and R. Goldbach and N. Zumstein and P. Vonmoos and J.-L. Scartezzini and A. Wirz-Justice and C. Cajochen},

url = {https://www.sciencedirect.com/science/article/pii/S2666354622001053},

doi = {https://doi.org/10.1016/j.bbih.2022.100515  },

year  = {2022},

date = {2022-09-20},

journal = {Brain, Behavior, & Immunity - Health},

volume = {26},

pages = {100515},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{JSR20220809,

title = {How to deal with sleep problems during heatwaves: practical recommendations from the European Insomnia Network},

author = {E. Altena and C. Baglioni and E. Sanz-Arigita and C. Cajochen and D. Riemann},

url = {https://onlinelibrary.wiley.com/doi/10.1111/jsr.13704},

doi = { https://doi.org/10.1111/jsr.13704},

year  = {2022},

date = {2022-09-08},

journal = {Journal of Sleep Research},

pages = {e13704},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{JAffDis0822,

title = {Influence of chronotype on the incidence and severity of perinatal depression in the "Life-ON" study },

author = {C. Garbazza and S. Hackethal and E. Migliore and A. D'Agostino and C. Serrati and V. Fanti and S. Riccardi and S. Baiardi and A. Cicolin and S. Borgwardt and S. Mondini and F. Cirignotta and C. Cajochen and M. Manconi and “Life-ON” study group

},

url = {https://www.sciencedirect.com/science/article/abs/pii/S016503272200920X?via%3Dihub},

doi = {https://doi.org/10.1016/j.jad.2022.08.064},

year  = {2022},

date = {2022-08-31},

journal = {Journal of Affective Disorders},

volume = {317},

pages = {245-255},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{AdvNutr,

title = {Chronotype differences in body composition, dietary intake and eating behavior outcomes - A scoping systematic review },

author = {C. van der Merwe and M. Münch and R. Kruger},

doi = {10.1093/advances/nmac093 },

year  = {2022},

date = {2022-08-30},

journal = {Advances in Nutrition},

volume = {13},

number = {6},

pages = {2357–2405},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Blume2022,

title = {Melatonin suppression does not automatically alter sleepiness, vigilance, sensory processing, or sleep},

author = {C. Blume and M. Niedernhuber and M. Spitschan and H. C. Slawik and M. P. Meyer and T. A. Bekinschtein and C. Cajochen},

doi = {https://doi.org/10.1093/sleep/zsac199},

year  = {2022},

date = {2022-08-23},

journal = {SLEEP},

abstract = {Pre-sleep exposure to short-wavelength light suppresses melatonin and decreases sleepiness with activating effects extending to sleep. This has mainly been attributed to melanopic effects, but mechanistic insights are missing. Thus, we investigated whether two light conditions only differing in the melanopic effects (123 vs. 59 lux melanopic EDI) differentially affect sleep besides melatonin. Additionally, we studied whether the light differentially modulates sensory processing during wakefulness and sleep.

Twenty-nine healthy volunteers (18-30 years, 15 women) were exposed to two metameric light conditions (high- vs. low-melanopic, ≈60 photopic lux) for 1 hour ending 50 min prior to habitual bed time. This was followed by an 8-h sleep opportunity with polysomnography. Objective sleep measurements were complemented by self-report. Salivary melatonin, subjective sleepiness, and behavioural vigilance were sampled at regular intervals. Sensory processing was evaluated during light exposure and sleep on the basis of neural responses related to violations of expectations in an oddball paradigm.

We observed suppression of melatonin by ≈14 % in the high- compared to the low-melanopic condition. However, conditions did not differentially affect sleep, sleep quality, sleepiness, or vigilance. A neural mismatch response was evident during all sleep stages, but not differentially modulated by light. Suppression of melatonin by light targeting the melanopic system does not automatically translate to acutely altered levels of vigilance or sleepiness or to changes in sleep, sleep quality, or basic sensory processing. Given contradicting earlier findings and the retinal anatomy, this may suggest that an interaction between melanopsin and cone-rod signals needs to be considered.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Garbazza_22,

title = {Sustained remission from perinatal depression after bright light therapy: a pilot randomised, placebo-controlled trial},

author = {C. Garbazza and F. Cirignotta and A. D'Agostino and A. Cicolin and S. Hackethal and A. Wirz-Justice and C. Cajochen and M. Manconi},

doi = {10.1111/acps.13482},

year  = {2022},

date = {2022-07-25},

journal = {Acta Psychiatr Scand},

volume = {146},

pages = {350–356.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ludwig22,

title = {Chronotherapy of affective disorders: principles and clinical aspects},

author = {VM. Ludwig and I. Münch and A. Wirz-Justice and P. Ritter 

},

doi = {doi: 10.1007/s00115-022-01323-0},

year  = {2022},

date = {2022-06-22},

journal = {Nervenarzt},

volume = {9},

pages = {892-900},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wislowska2022,

title = {Sleep-specific processing of auditory stimuli is reflected by alpha and sigma oscillations},

author = {M. Wislowska and W. Klimesch and O. Jensen and C. Blume and M. Schabus},

doi = {https://doi.org/10.1523/JNEUROSCI.1889-21.2022 },

year  = {2022},

date = {2022-06-08},

journal = {Journal of Neuroscience},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Reichert2022,

title = {Adenosine, caffeine, and sleep–wake regulation: state of the science and perspectives},

author = {C. F. Reichert and T. Deboer and H.-P. Landolt},

url = {http://www.chronobiology.ch/reichert-2022-adenosine-caffeine-sleep-review-2/},

doi = {10.1111/jsr.13597},

year  = {2022},

date = {2022-05-16},

journal = {Journal of Sleep Research},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Gibson2022,

title = { Sleeping in a bubble: factors affecting sleep during New Zealand’s COVID-19 lockdown },

author = {R. Gibson and H. Shetty and M. Carter and M. Münch},

url = {https://academic.oup.com/sleepadvances/article/3/1/zpac017/6586527?login=false},

doi = {https://doi.org/10.1093},

year  = {2022},

date = {2022-05-16},

journal = {Sleep Advances},

volume = {3},

number = {1},

pages = {zpac017},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sleep0422,

title = {Cross-sectional study of intraocular cataract lens replacement, circadian rest-activity rhythms, and sleep quality in older adults},

author = {

S.L. Chellappa and V. Bromundt and S. Frey and T. Schlote and D. Goldblum and C. Cajochen 

},

url = {https://academic.oup.com/sleep/article-abstract/45/4/zsac027/6515911?redirectedFrom=fulltext&login=false},

doi = {10.1093/sleep/zsac027. },

year  = {2022},

date = {2022-04-11},

journal = {Sleep},

volume = {45},

number = {4},

pages = {zsac027},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{TM2022,

title = {Recommendations for daytime, evening, and nighttime indoor light exposure to best support physiology, sleep, and wakefulness in healthy adults},

author = {TM Brown and GC Brainard and C Cajochen and CA Czeisler and JP Hanifin and SW Lockley and RJ Lucas and M Münch and JB O'Hagan and SN Peirson and LLA Price and T Roenneberg and LJM Schlangen and DJ Skene and M Spitschan and C Vetter and PC Zee and KP Jr Wright},

doi = {10.1371/journal.pbio.3001571},

year  = {2022},

date = {2022-03-17},

journal = {PLoS Biology},

volume = {20},

number = {3},

pages = {e3001571},

abstract = {Ocular light exposure has important influences on human health and well-being through modulation of circadian rhythms and sleep, as well as neuroendocrine and cognitive functions. Prevailing patterns of light exposure do not optimally engage these actions for many individuals, but advances in our understanding of the underpinning mechanisms and emerging lighting technologies now present opportunities to adjust lighting to promote optimal physical and mental health and performance. A newly developed, international standard provides a SI-compliant way of quantifying the influence of light on the intrinsically photosensitive, melanopsin-expressing, retinal neurons that mediate these effects. The present report provides recommendations for lighting, based on an expert scientific consensus and expressed in an easily measured quantity (melanopic equivalent daylight illuminance (melaponic EDI)) defined within this standard. The recommendations are supported by detailed analysis of the sensitivity of human circadian, neuroendocrine, and alerting responses to ocular light and provide a straightforward framework to inform lighting design and practice. },

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Angerer2022,

title = {From Dawn to Dusk – Mimicking Natural Daylight Exposure Improves Circadian Rhythm Entrainment in Patients with Severe Brain Injury},

author = {M. Angerer and M. Schabus and G. Pichler and B. Angerer and M. Scarpatetti and C. Blume},

doi = {https://doi.org/10.1093/sleep/zsac065},

year  = {2022},

date = {2022-03-16},

journal = {SLEEP},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Angerer2022b,

title = {Does the Heart Fall Asleep? - Diurnal Variations of Heart Rate Variability in Patients with Disorders of Consciousness.},

author = {M. Angerer and F.H. Wilhelm and M. Liedlgruber and G. Pichler and B. Angerer and M. Scarpatetti and C. Blume and M. Schabus},

doi = {https://doi.org/10.3390/brainsci12030375 },

year  = {2022},

date = {2022-03-14},

journal = {Brain Sciences},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Benedetti2022,

title = {Optimized office lighting advances melatonin phase and peripheral heat loss prior bedtime},

author = {M. Benedetti and L. Maierová and C. Cajochen and J.-L. Scartezzini and M. Münch},

url = {https://www.nature.com/articles/s41598-022-07522-8},

doi = {https://doi.org/10.1038/s41598-022-07522-8},

year  = {2022},

date = {2022-03-11},

journal = {Scientific Reports},

volume = {12},

pages = {4267},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{C&S0222,

title = { Circadian and sleep modulation of dreaming in women with major depression},

author = {A. Birchler-Pedross and S. Frey and C. Cajochen and S.L. Chellappa 

},

url = {https://www.mdpi.com/2624-5175/4/1/12},

doi = {10.3390/clockssleep4010012 },

year  = {2022},

date = {2022-02-28},

journal = {Clocks & Sleep},

volume = {4},

number = {1},

pages = {114-128},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lin2022,

title = {Time to recover from daily caffeine intake},

author = {Y.-S. Lin and J. Weibel and H.-P. Landolt and F Santini and C Garbazza and J Kistler and S Rehm and K Rentsch and S Borgwardt and C Cajochen and C. F. Reichert},

url = {https://www.frontiersin.org/articles/10.3389/fnut.2021.787225/full},

doi = {10.3389/fnut.2021.787225. },

year  = {2022},

date = {2022-02-02},

journal = {Front Nutr.},

volume = {8},

number = {787225},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{AWJ_MT_2022,

title = { CME: Light therapy: Why, what, for whom, how, and when (and a postscript about darkness). },

author = {A. Wirz-Justice and AM. Terman},

doi = {10.1024/1661-8157/a003821 },

year  = {2022},

date = {2022-02-01},

journal = {Praxis (Bern 1994)},

volume = {110},

number = {2},

pages = {56-62},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Ameen2022,

title = {The brain selectively tunes to unfamiliar voices during sleep},

author = {M.S. Ameen and D.P.J. Heib and C. Blume and M. Schabus},

doi = {https://doi.org/10.1523/JNEUROSCI.2524-20.2021},

year  = {2022},

date = {2022-01-17},

journal = {Journal of Neuroscience},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Cajochen2022,

title = {Influence of evening light exposure on polysomnographically assessed night-time sleep: A systematic review with meta-analysis },

author = {C. Cajochen and O. Stefani and I. Schöllhorn and D. Lang and S. Chellappa},

doi = {https://doi.org/10.1177/14771535221078765},

year  = {2022},

date = {2022-01-10},

urldate = {2022-01-10},

journal = {Lighting Research & Technology},

volume = {54},

pages = {609-654},

abstract = {Evening exposure to electric light can acutely suppress melatonin levels and adversely affect subsequent sleep. We conducted a systematic review with meta-analysis investigating the influence of evening illuminance levels on polysomnographically (PSG)-assessed sleep. We also explored how melanopsin (expressed in melanopic equivalent daylight illuminance (EDI) affects human sleep features. We included polysomnographic laboratory sleep studies with healthy humans for effects of illuminance and exposure duration, for pre-sleep exposures between 6:00 p.m. to 1:00 a.m. From 440 identified articles, 114 met eligibility criteria for screening, and 21 also reported type of light source/spectral characteristics, with 12 identified as eligible for review. Meta-analysis showed evening light affects sleep latency, sleep efficiency and slow wave sleep, with overall effect sizes (95% confidence interval) of 0.69 (−0.50; 1.88), 0.34 (−0.13; 0.82) and −0.61 (−1.85; 0.62), respectively. Estimated melanopic EDI in the range of 100–1000 lx yielded clear dose–response relationships for sleep latency and sleep efficiency, but not for slow wave sleep. Whilst illuminance and duration indicated no apparent effects for a single evening light exposure on PSG-assessed sleep latency, sleep efficiency and slow wave sleep, we observed evidence for a relationship between light exposure and sleep effects based on melanopic EDI. Hence, melanopic EDI may provide a robust predictor of non-visual responses on human sleep.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Gimenez2022,

title = {Predicting melatonin suppression by light in humans: unifying photoreceptor-based equivalent daylight illuminances, spectral composition, timing and duration of light exposure},

author = {M. Gimenez and O. Stefani and C. Cajochen and D. Lang and G. Deuring and L.J.M. Schlangen},

doi = { https://doi.org/10.1111/jpi.12786},

year  = {2022},

date = {2022-01-03},

journal = {Journal of Pineal Research},

abstract = {Light-induced melatonin suppression data from 29 peer-reviewed publications was analysed by means of a machine learning approach to establish which light exposure characteristics (i.e. photopic illuminance, five α-opic equivalent daylight illuminances (EDIs), duration and timing of the light exposure, and the dichotomous variables pharmacological pupil dilation and narrowband light source) are the main determinants of melatonin suppression. Melatonin suppression in the dataset was dominated by four light exposure characteristics: 1. melanopic EDI, 2. light exposure duration, 3. pupil dilation and 4. S-cone-opic EDI. A logistic model was used to evaluate the influence of each of these parameters on the melatonin suppression response. The final logistic model was only based on the first three parameters, since melanopic EDI was the best single (photoreceptor) predictor that was only outperformed by S-cone-opic EDI for (photopic) illuminances below 21 lux. This confirms and extends findings on the importance of the metric melanopic EDI for predicting biological effects of light in integrative (human centric) lighting applications. The model provides initial and general guidance to lighting practitioners on how to combine spectrum, duration and amount of light exposure when controlling non-visual responses to light, especially melatonin suppression. The model is a starting tool for developing hypotheses on photoreceptors’ contributions to light’s non-visual responses and helps identifying areas where more data is needed, like on the S-cone contribution at low illuminances.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lazar.2022,

title = {Light flash therapy in the wild},

author = {R. Lazar},

url = {https://rdcu.be/cQH7W},

doi = {10.1038/s44159-022-00084-6},

issn = {2731-0574},

year  = {2022},

date = {2022-01-01},

journal = {Nature Reviews Psychology},

abstract = {In this Journal Club, Rafael Lazar describes a randomized field trial that tested whether light flash therapy improves the duration and timing of sleep in adolescents.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{McCarthy21,

title = {Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: A critical multi-disciplinary literature review and agenda for future research from the ISBD task force on chronobiology},

author = {MJ. McCarthy and JF. Gottlieb and R. Gonzalez and CA. McClung and LB. Alloy and S. Cain and D. Dulcis and B. Etain and BN. Frey and C. Garbazza and KD. Ketchesin and D. Landgraf and HJ. Lee and C. Marie-Claire and R. Nusslock and A. Porcu and R. Porter and P. Ritter and J. Scott and D. Smith and HA. Swartz and G. Murray},

doi = {10.1111/bdi.13165. },

year  = {2021},

date = {2021-12-10},

journal = {Bipolar Disorders},

volume = {24},

number = {3},

pages = {232-263},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Zandi2021,

title = {Optimising metameric spectra for integrative lighting to modulate the circadian system without affecting visual appearance},

author = {B. Zandi and O. Stefani and A. Herzog and L. Schlangen and Q. Trinh and T. Khanh },

url = {https://www.nature.com/articles/s41598-021-02136-y},

doi = {https://doi.org/10.1038/s41598-021-02136-y},

year  = {2021},

date = {2021-11-30},

journal = {Scientific Reports},

volume = {11},

number = {23188},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{BrBehImm2021,

title = {Circadian and homeostatic sleep-wake regulation of secretory immunoglobulin A (sIgA): Effects of environmental light and recovery sleep},

author = {C. Cajochen and J. Weber and A.J. Estrada and K. Kobayashi and V. Gabel 

},

url = {https://www.sciencedirect.com/science/article/pii/S2666354621001976?via%3Dihub},

doi = {10.1016/j.bbih.2021.100394 },

year  = {2021},

date = {2021-11-23},

journal = {Brain, Behaviour, Immunity, & Health},

pages = { 100394},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{33129807,

title = {The relevance of daylight for humans},

author = {Wirz-Justice A, Skene DJ, Münch M. },

doi = {https://doi.org/10.1016/j.bcp.2020.114304},

year  = {2021},

date = {2021-09-01},

journal = {Biochem Pharmacol},

pages = {191},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Knaier2021,

title = {Diurnal Variation in Maximum Endurance and Maximum Strength Performance: A Systematic Review and Meta-analysis.},

author = {R Knaier and J Qian and R Roth and D Infanger and T Notter and W Wang and C Cajochen and FAJL Scheer},

doi = {10.1249/mss.0000000000002773},

year  = {2021},

date = {2021-08-24},

journal = {Medicine and Science in Sports and Exercise},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Eze2021,

title = {Incidence of depression in relation to transportation noise exposure and noise annoyance in the SAPALDIA study},

author = {I C Eze and M Foraster and E Schaffner and D Vienneau and R Pieren and M Imboden and J-M Wunderli and C Cajochen and M Brinki and M Röösli and N Probst-Hensch},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/1-s2.0-S0160412020319693-main.pdf},

doi = {10.1016/j.envint.2020.106014},

year  = {2021},

date = {2021-08-04},

journal = {Environ Int.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Blume2021b,

title = {Association of transportation noise with sleep during the first year of life: a longitudinal study},

author = {C. Blume and S. F. Schoch and D. Vienneau and M. Röösli and M. Kohler and A. Moeller and S. Kurth and J. Usemann},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/1-s2.0-S0013935121010707-main.pdf},

doi = {https://doi.org/10.1016/j.envres.2021.111776},

year  = {2021},

date = {2021-07-28},

journal = {Environmental Research},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Bahr2021,

title = {With #IchBinHanna, German academia protests against a law that forces researchers out},

author = {A. Bahr and C. Blume and K. Eichhorn and S. Kubon},

doi = {https://doi.org/10.1038/s41562-021-01178-6},

year  = {2021},

date = {2021-07-22},

journal = {Nature Human Behaviour},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Spitschan2021,

title = {Sleep and circadian phenotype in people without cone-mediated vision: a case series of five CNGB3 and two CNGA3 patients},

author = {M. Spitschan and C. Garbazza and S. Kohl and C. Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/fcab159.pdf},

doi = {10.1093/braincomms/fcab159},

year  = {2021},

date = {2021-07-18},

journal = {Brain Communications},

abstract = {Light exposure entrains the circadian clock through the intrinsically photosensitive retinal ganglion cells, which sense light in addition to the cone and rod photoreceptors. In congenital achromatopsia (prevalence 1:30–50 000), the cone system is non-functional, resulting in severe light avoidance and photophobia at daytime light levels. How this condition affects circadian and neuroendocrine responses to light is not known. In this case series of genetically confirmed congenital achromatopsia patients (n = 7; age 30–72 years; 6 women, 1 male), we examined survey-assessed sleep/circadian phenotype, self-reported visual function, sensitivity to light and use of spectral filters that modify chronic light exposure. In all but one patient, we measured rest-activity cycles using actigraphy over 3 weeks and measured the melatonin phase angle of entrainment using the dim-light melatonin onset. Owing to their light sensitivity, congenital achromatopsia patients used filters to reduce retinal illumination. Thus, congenital achromatopsia patients experienced severely attenuated light exposure. In aggregate, we found a tendency to a late chronotype. We found regular rest-activity patterns in all patients and normal phase angles of entrainment in participants with a measurable dim-light melatonin onset. Our results reveal that a functional cone system and exposure to daytime light intensities are not necessary for regular behavioural and hormonal entrainment, even when survey-assessed sleep and circadian phenotype indicated a tendency for a late chronotype and sleep problems in our congenital achromatopsia cohort.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Weibel2021b,

title = {Regular caffeine intake delays REM sleep promotion and attenuates sleep quality in healthy men},

author = {J. Weibel and Y.-S. Lin and H.-P. Landolt and C. Berthomier and M. Brandenwinder and J. Kistler and S. Rehm and K. Rentsch and M. Meyer and S. Borgwardt and C. Cajochen and C. F. Reichert },

url = {https://journals.sagepub.com/doi/pdf/10.1177/07487304211013995},

doi = {10.1177/07487304211013995},

year  = {2021},

date = {2021-05-23},

journal = {Journal of Biological Rhythms},

abstract = {Acute  caffeine  intake  can  attenuate  homeostatic  sleep  pressure  and  worsen  sleep  quality.  Caffeine  intake—particularly  in  high  doses  and  close  to  bedtime—may  also  affect  circadian-regulated  rapid  eye  movement  (REM)  sleep  promotion,  an  important  determinant  of  subjective  sleep  quality.  However,  it  is  not  known  whether  such  changes  persist  under  chronic  caffeine  consumption  during  daytime.  Twenty  male  caffeine  consumers  (26.4  ±  4  years  old,  habitual  caffeine  intake  478.1  ±  102.8  mg/day)  participated  in  a  double-blind  crossover  study. Each volunteer completed a caffeine (3 × 150 mg caffeine daily for 10 days), a withdrawal (3 × 150 mg caffeine for 8 days then placebo), and a placebo condition. After 10 days of controlled intake and a fixed sleep-wake cycle, we recorded electroencephalography  for  8  h  starting  5  h  after  habitual  bedtime  (i.e.,  start  on  average at 04:22 h which is around the peak of circadian REM sleep promotion). A 60-min evening nap preceded each sleep episode and reduced high sleep pres-sure levels. While total sleep time and sleep architecture did not significantly differ between the three conditions, REM sleep latency was longer after daily caffeine intake compared with both placebo and withdrawal. Moreover, the accumulation of REM sleep proportion was delayed, and volunteers reported more difficulties with awakening after sleep and feeling more tired upon wake-up in the caffeine condition  compared  with  placebo.  Our  data  indicate  that  besides  acute  intake,  also  regular  daytime  caffeine  intake  affects  REM  sleep  regulation  in  men,  such  that  it  delays  circadian  REM  sleep  promotion  when  compared  with  placebo.  Moreover, the observed caffeine-induced deterioration in the quality of awakening may suggest a potential motive to reinstate caffeine intake after sleep.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Stefani2021,

title = {Should We Re-think Regulations and Standards for Lighting at Workplaces? A Practice Review on Existing Lighting Recommendations},

author = {O. Stefani and C. Cajochen },

editor = {S. Rahman

},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/fpsyt-12-652161.pdf},

doi = {10.3389/fpsyt.2021.652161},

year  = {2021},

date = {2021-05-13},

journal = {Frontiers in psychiatry},

volume = {12},

abstract = {Nowadays lighting projects often include temporal variations of the light, both spectrally

and in terms of intensity to consider non-visual effects of light on people. However, as

of today there are no specific regulations. Compliance with common lighting standards

that address visual aspects of light, often means that only little non-visually effective

light reaches the eye. In this practice review we confront existing regulations and

standards on visual lighting aspects with new recommendations on non-visual aspects

and highlight conflicts among them. We conclude with lighting recommendations that

address both aspects},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wielek2021,

title = {Decoding brain responses to names and voices across different vigilance states},

author = {T. Wielek and C. Blume and M. Wislowska and R. del Giudice and M. Schabus},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/sensors-21-03393.pdf},

doi = {https://doi.org/10.3390/s21103393},

year  = {2021},

date = {2021-05-07},

journal = {Sensors},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Blume2021c,

title = {‘SleepCycles’ package for R - A free software tool for the detection of sleep cycles from sleep staging},

author = {C Blume and C Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/main.pdf},

doi = {https://doi.org/10.1016/j.mex.2021.101318},

year  = {2021},

date = {2021-04-06},

journal = {MethodsX},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Blume2021,

title = {‘SleepCycles’ package for R - A free software tool for the detection of sleep cycles from sleep staging},

author = {C. Blume and C. Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/main.pdf},

doi = {https://doi.org/10.1016/j.mex.2021.101318},

year  = {2021},

date = {2021-04-06},

journal = {MethodsX},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Weibel2021c,

title = {The impact of daily caffeine intake on nighttime sleep in young adult men},

author = {J.. Weibel and Y-S Lin and H-P Landolt and J Kistler and S Rehm and K M Rentsch and H Slawik and S Borgwardt and C Cajochen and C F Reichert},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/41598_2021_Article_84088.pdf},

doi = {10.1038/s41598-021-84088-x},

year  = {2021},

date = {2021-02-25},

journal = {Sci Rep.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Lin2021,

title = {Daily Caffeine Intake Induces Concentration-Dependent Medial Temporal Plasticity in Humans: A Multimodal Double-Blind Randomized Controlled Trial },

author = { Y.-S. Lin and J. Weibel and H. Landolt and F. Santini and M. Meyer and J. Brunmair and S. Meyer-Menches and C. gerner and S. Borgwardt and C. Cajochen and C. F. Reichert},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/02/Lin_2021_CC_acc_uncorrect.pdf},

doi = {doi.org/10.1093/cercor/bhab005},

year  = {2021},

date = {2021-02-15},

journal = {Cerebral Cortex},

abstract = {Caffeine is commonly used to combat high sleep pressure on a daily basis. However, interference with sleep–wake regulation could disturb neural homeostasis and insufficient sleep could lead to alterations in human gray matter. Hence, in this double-blind, randomized, cross-over study, we examined the impact of 10-day caffeine (3 × 150 mg/day) on human gray matter volumes (GMVs) and cerebral blood flow (CBF) by fMRI MP-RAGE and arterial spin-labeling sequences in 20 habitual caffeine consumers, compared with 10-day placebo (3 × 150 mg/day). Sleep pressure was quantified by electroencephalographic slow-wave activity (SWA) in the previous nighttime sleep. Nonparametric voxel-based analyses revealed a significant reduction in GMV in the medial temporal lobe (mTL) after 10 days of caffeine intake compared with 10 days of placebo, voxel-wisely adjusted for CBF considering the decreased perfusion after caffeine intake compared with placebo. Larger GMV reductions were associated with higher individual concentrations of caffeine and paraxanthine. Sleep SWA was, however, neither different between conditions nor associated with caffeine-induced GMV reductions. Therefore, the data do not suggest a link between sleep depth during daily caffeine intake and changes in brain morphology. In conclusion, daily caffeine intake might induce neural plasticity in the mTL depending on individual metabolic processes.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wagner2021,

title = {Verification-phase tests show low reliability and add little value in determining V˙O2max in young trained adults},

author = {J Wagner and M Niemeyer and D Infanger and T Hinrichs and C Guerra and C Klenk and K Königstein and C Cajochen and A Schmidt-Trucksäss and R Knaier},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/pone.0245306.pdf},

doi = {10.1371/journal.pone.0245306},

year  = {2021},

date = {2021-01-11},

journal = {PlosOne},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{ries2021annexin,

title = {Annexin A1 restores cerebrovascular integrity concomitant with reduced amyloid-beta and tau pathology},

author = {Miriam Ries and Helena Watts and Bibiana C Mota and Maria Yanez Lopez and Cornelius K Donat and Nicoleta Baxan and James A Pickering and Tsz Wing Chau and Annika Semmler and Brinda Gurung and others},

year  = {2021},

date = {2021-01-01},

journal = {Brain},

volume = {144},

number = {5},

pages = {1526--1541},

publisher = {Oxford University Press},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Stefani2020,

title = {Changing color and intensity of LED lighting across the day impacts on circadian melatonin rhythms and sleep in healthy men},

author = {O. Stefani and M. Freyburger and S. Veitz and T. Basishvili and M. Meyer and J. Weibel and K. Kobayashi and Y. Shirakawa and C. Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/Changing-color-and-intensity-of-LED-lighting-across-the-day-impacts-on-circadian-melatonin-rhythms-and-sleep-in-healthy-men.pdf},

doi = {10.1111/jpi.12714},

year  = {2020},

date = {2020-12-30},

journal = {Journal of Pineal Research},

volume = {70},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Reichert2020,

title = {Wide awake at bedtime? The effects of caffeine on sleep and circadian timing in teenagers - a randomized crossover trial.},

author = {C. F. Reichert and S. Veitz and M. Bühler and G. Gruber and G. Deuring and S. S. Rehm, K. Rentsch and C. Garbazza and M. Meyer and H. Slawik and Y.-S. Lin and J. Weibel},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/1-s2.0-S0006295220305190-main.pdf},

doi = {https://doi.org/10.1016/j.bcp.2020.114283},

year  = {2020},

date = {2020-10-15},

journal = {Biochemical Pharmacology},

abstract = {Adolescents often suffer from short and mistimed sleep. To counteract the resulting daytime sleepiness they frequently consume caffeine. However, caffeine intake may exaggerate sleep problems by disturbing sleep and circadian timing. In a 28-hour double-blind randomized crossover study, we investigated to what extent caffeine disturbs slow-wave sleep (SWS) and delays circadian timing in teenagers. Following a 6-day ambulatory phase of caffeine abstinence and fixed sleep-wake cycles, 18 male teenagers (14–17 years old) ingested 80 mg caffeine vs. placebo in the laboratory four hours prior to an electro-encephalographically (EEG) recorded nighttime sleep episode. Data were analyzed using both frequentist and Bayesian statistics. The analyses suggest that subjective sleepiness is reduced after caffeine compared to placebo. However, we did not observe a strong caffeine-induced reduction in subjective sleep quality or SWS, but rather a high inter-individual variability in caffeine-induced SWS changes. Exploratory analyses suggest that particularly those individuals with a higher level of SWS during placebo reduced SWS in response to caffeine. Regarding salivary melatonin onsets, caffeine-induced delays were not evident at group level, and only observed in participants exposed to a higher caffeine dose relative to individual bodyweight (i.e., a dose > 1.3 mg/kg). Together, the results suggest that 80 mg caffeine are sufficient to induce alertness at a subjective level. However, particularly teenagers with a strong need for deep sleep might pay for these subjective benefits by a loss of SWS during the night. Thus, caffeine-induced sleep-disruptions might change along with the maturation of sleep need.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Cerletti2020,

title = {The independent association of source-specific transportation noise exposure, noise annoyance and noise sensitivity with health-related quality of life},

author = {P Cerletti and I C Eze and E Schaffner and M Foraster and D Viennau and C Cajochen and J-M Wunderli and M Röösli and D Stolz and M Pons and M Imboden and N Probst-Hensch},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/1-s2.0-S0160412020319152-main.pdf},

doi = {10.1016/j.envint.2020.105960},

year  = {2020},

date = {2020-10-01},

journal = {Environ Int.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Spitschan2020,

title = {Transparency and open science principles in reporting guidelines in sleep research and chronobiology journals},

author = {M. Spitschan and Marlene H. Schmidt and C. Blume},

doi = {https://doi.org/10.12688/wellcomeopenres.16111.1},

year  = {2020},

date = {2020-07-20},

journal = {Wellcome Open Research},

abstract = {Background: "Open science" is an umbrella term describing various aspects of transparent and open science practices. The adoption of practices at different levels of the scientific process (e.g., individual researchers, laboratories, institutions) has been rapidly changing the scientific research landscape in the past years, but their uptake differs from discipline to discipline. Here, we asked to what extent journals in the field of sleep research and chronobiology encourage or even require following transparent and open science principles in their author guidelines.

Methods: We scored the author guidelines of a comprehensive set of 28 sleep and chronobiology journals, including the major outlets in the field, using the standardised Transparency and Openness (TOP) Factor. This instrument rates the extent to which journals encourage or require following various aspects of open science, including data citation, data transparency, analysis code transparency, materials transparency, design and analysis guidelines, study pre-registration, analysis plan pre-registration, replication, registered reports, and the use of open science badges.

Results: Across the 28 journals, we find low values on the TOP Factor (median [25th, 75th percentile] 2.5 [1, 3], min. 0, max. 9, out of a total possible score of 28) in sleep research and chronobiology journals.

Conclusions: Our findings suggest an opportunity for sleep research and chronobiology journals to further support the recent developments in transparent and open science by implementing transparency and openness principles in their guidelines and making adherence to them mandatory.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Chylinski2020,

title = {Validation of an Automatic Arousal Detection Algorithm for Whole-Night Sleep EEG Recordings},

author = {D Chylinski and F Rudzik and D C ‘t Wallant and M Grignard and N Vandeleene and M Van Egroo and L Thiesse and S Solbach and P Maquet and C Phillips and G Vandewalle and C Cajochen and V Muto},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/clockssleep-02-00020.pdf},

doi = {10.3390/clockssleep2030020},

year  = {2020},

date = {2020-07-16},

journal = {Clocks Sleep},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Blume2020c,

title = {When the girdle of social timing relaxes: Effects of the COVID-19 lockdown on human sleep},

author = {C. Blume and Marlene H. Schmidt},

url = {https://thesciencebreaker.org/breaks/psychology/when-the-girdle-of-social-timing-relaxes-effects-of-the-covid-19-lockdown-on-human-sleep},

doi = {https://doi.org/10.25250/thescbr.brk363},

year  = {2020},

date = {2020-07-09},

journal = {The Science Breaker},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Blume2020bb,

title = {Effects of the COVID-19 lockdown on human sleep and rest-activity rhythms},

author = {C Blume and Marlene H Schmidt and C Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/1-s2.0-S096098222030837X-main.pdf},

doi = {https://doi.org/10.1016/j.cub.2020.06.021},

year  = {2020},

date = {2020-06-10},

journal = {Current Biology},

abstract = {In modern societies, human rest-activity rhythms and sleep result from the tensions and dynamics between the conflicting poles of external social time (e.g., work hours and leisure activities) and an individual’s internal biological time. A mismatch between the two has been suggested to induce ‘social jetlag’ [SJL; 1] and ‘social sleep restriction’ (SSR), that is, shifts in sleep timing and differences in sleep duration between work days and free days. Social jetlag [2, 3] and sleep restrictions [4] have repeatedly been associated with negative consequences on health, mental wellbeing, and performance. In a large-scale quasi-experimental design, we investigated the effects of the phase with the strictest COVID-19 restrictions on the relationship between social and biological rhythms as well as sleep during a six-week period (mid-March until end of April 2020) in three European societies (Austria, Germany, Switzerland). We found that, on one hand, the restrictions reduced the mismatch between external (social) and internal (biological) sleep-wake timing, as indexed by significant reductions in SJL and SSR, with a concomitant increase in sleep duration. Sleep quality on the other hand was slightly reduced. The improved individual sleep-wake timing can presumably be attributed to an increased flexibility of social schedules, for instance due to more work being accomplished from home. However, this unprecedented situation also led to a significant increase in self-perceived burden, which was attendant to the decrease in sleep quality. These adverse effects may be alleviated by exposure to natural daylight as well as physical exercising.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Blume2020b,

title = {Effects of the COVID-19 lockdown on human sleep and rest-activity rhythms},

author = {C. Blume and Marlene H. Schmidt and C. Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/1-s2.0-S096098222030837X-main.pdf},

doi = {https://doi.org/10.1016/j.cub.2020.06.021},

year  = {2020},

date = {2020-06-10},

journal = {Current Biology},

abstract = {In modern societies, human rest-activity rhythms and sleep result from the tensions and dynamics between the conflicting poles of external social time (e.g., work hours and leisure activities) and an individual’s internal biological time. A mismatch between the two has been suggested to induce ‘social jetlag’ [SJL; 1] and ‘social sleep restriction’ (SSR), that is, shifts in sleep timing and differences in sleep duration between work days and free days. Social jetlag [2, 3] and sleep restrictions [4] have repeatedly been associated with negative consequences on health, mental wellbeing, and performance. In a large-scale quasi-experimental design, we investigated the effects of the phase with the strictest COVID-19 restrictions on the relationship between social and biological rhythms as well as sleep during a six-week period (mid-March until end of April 2020) in three European societies (Austria, Germany, Switzerland). We found that, on one hand, the restrictions reduced the mismatch between external (social) and internal (biological) sleep-wake timing, as indexed by significant reductions in SJL and SSR, with a concomitant increase in sleep duration. Sleep quality on the other hand was slightly reduced. The improved individual sleep-wake timing can presumably be attributed to an increased flexibility of social schedules, for instance due to more work being accomplished from home. However, this unprecedented situation also led to a significant increase in self-perceived burden, which was attendant to the decrease in sleep quality. These adverse effects may be alleviated by exposure to natural daylight as well as physical exercising.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Eze2020,

title = {Genome-Wide DNA Methylation in Peripheral Blood and Long-Term Exposure to Source-Specific Transportation Noise and Air Pollution: The SAPALDIA Study},

author = {I. C. Eze and A. Jeong and E. Schaffner and F. I. Rezwan and A. Ghantous and M. Foraster and D. Vienneau and F. Kronenberg F and Z. Herceg and P. Vineis and M. Brink and J. M. Wunderli and C. Schindler and C. Cajochen and M. Röösli M and J. W. Holloway and M. Imboden and N. Probst-Hensch},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/06/EHP6174.pdf},

year  = {2020},

date = {2020-06-01},

journal = {Environ Health Perspect},

volume = {128},

number = {6},

pages = {67003},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Angerer2020,

title = {Actigraphy in brain-injured patients – A valid measurement for assessing circadian rhythms?},

author = {M. Angerer and M. Schabus and M. Raml and G. Pichler and A. B. Kunz and M. Scarpatetti and E. Trinka and C. Blume},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/05/s12916-020-01569-y.pdf},

doi = {10.1186/s12916-020-01569-y},

year  = {2020},

date = {2020-05-12},

journal = {BMC Medicine},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hollinger2020,

title = {Study Protocol for a Prospective Randomised Double-Blind Placebo-Controlled Clinical Trial Investigating a Better Outcome With Melatonin Compared to Placebo Administered to Normalize Sleep-Wake Cycle and Treat Hypoactive ICU Delirium: The Basel BOMP-AID Study},

author = {A. Hollinger and S. von Felten and R. Sutter and J. Huber and F. Tran and S. Reinhold and S. Abdelhamid and A. Todorov and C. E. Gebhard and C. Cajochen and L. A Steiner and M. Siegemund},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/05/e034873.full_.pdf},

doi = {10.1136/bmjopen-2019-034873},

year  = {2020},

date = {2020-04-30},

journal = {BMJ Open},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Weibel2020,

title = {Caffeine-dependent changes of sleep-wake regulation: Evidence foradaptation after repeated intake},

author = {J. Weibel and Y.-S. Lin and H.-P. Landolt and C. Garbazza and V. Kolodyazhniy and J. Kistler and S. Rehm and K. Rentsch and S. Borgwardt and C. Cajochen and C. F. Reichert },

url = {http://www.chronobiology.ch/1-s2-0-s0278584619304798-main-2/},

doi = {10.1016/j.pnpbp.2019.109851 },

year  = {2020},

date = {2020-04-20},

journal = {Progress in Neuro-Psychopharmacology and Biological Psychiatry},

abstract = {Background: Circadian and sleep-homeostatic mechanisms regulate timing and quality of wakefulness. To enhance wakefulness, daily consumption of caffeine in the morning and afternoon is highly common. However, the effects of such a regular intake pattern on circadian sleep-wake regulation are unknown. Thus, we investigated if daily daytime caffeine intake and caffeine withdrawal affect circadian rhythms and wake-promotion in habitual consumers.

Methods: Twenty male young volunteers participated in a randomised, double-blind, within-subject study with three conditions: i) caffeine (150 mg 3 x daily for 10 days), ii) placebo (3 x daily for 10 days) and iii) withdrawal (150 mg caffeine 3 x daily for eight days, followed by a switch to placebo for two days). Starting on day nine of treatment, salivary melatonin and cortisol, evening nap sleep as well as sleepiness and vigilance performance throughout day and night were quantified during 43 h in an in-laboratory, light and posture-controlled protocol.

Results: Neither the time course of melatonin (i.e. onset, amplitude or area under the curve) nor the time course of cortisol was significantly affected by caffeine or withdrawal. During withdrawal, however, volunteers reported increased sleepiness, showed more attentional lapses as well as polysomnography-derived markers of elevated sleep propensity in the late evening compared to both the placebo and caffeine condition.

Conclusions: The typical pattern of caffeine intake with consumption in both the morning and afternoon hours may not necessarily result in a circadian phase shift in the evening nor lead to clear-cut benefits in alertness. The time-of-day independent effects of caffeine withdrawal on evening nap sleep, sleepiness and performance suggest an adaptation to the substance, presumably in the homeostatic aspect of sleep-wake regulation.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Chellappa2020,

title = {Intraocular cataract lens replacement and light exposure potentially impact procedural learning in older adults},

author = {S. L. Chellappa and V. Bromundt and S. Frey and T. Schlote and

D. Goldblum and C. Cajochen and C. F. Reichert},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/04/Chellappa-et-al.-JSR_2020.pdf},

doi = {10.1111/jsr.13043},

year  = {2020},

date = {2020-04-14},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Münch2020db,

title = {The Role of Daylight for Humans: Gaps in Current Knowledge},

author = {M Münch and A Wirz-Justice and S A Brown and T Kantermann and K Martiny and O Stefani and C Vetter and Wright K P Jr and K Wulff and D J Skene},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/02/clockssleep-02-00008.pdf},

doi = {10.3390/clockssleep2010008},

year  = {2020},

date = {2020-02-28},

journal = {Clocks & Sleep},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Rudzik2020,

title = {Ultradian Modulation of Cortical Arousals During Sleep: Effects of Age and Exposure to Nighttime Transportation Noise},

author = {F. Rudzik and L. Thiesse and R. Pieren and H. Héritier and I. C Eze and M. Foraster and D. Vienneau and M. Brink and J. M. Wunderli and N. Probst-Hensch and M. Röösli and S. Fulda and C. Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/05/zsz324.pdf},

doi = {10.1093/sleep/zsz324},

year  = {2020},

date = {2020-02-26},

journal = {Sleep},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Caviezel2020,

title = {The Neural Mechanisms of Associative Memory Revisited: fMRI Evidence from Implicit Contingency Learning},

author = {M. P. Caviezel and C. F. Reichert and D. S. Bahmani and C. Linnemann and C. Liechti and O. Bieri and S. Borgwardt and T. Leyhe and T. Melcher},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/03/fpsyt-10-01002.pdf},

doi = {10.3389/fpsyt.2019.01002},

year  = {2020},

date = {2020-02-03},

journal = {Front. Psychiatry},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Blume2020,

title = {Perspective: Daylight Saving Time—An Advocacy for a Balanced View and against Fanning Fear},

author = {C. Blume and M. Schabus},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/02/Blume-2020-Perspective-Daylight-Saving-Time-Advocacy-for-Balanced-Perspective.pdf},

doi = {10.3390/clockssleep2010003},

year  = {2020},

date = {2020-01-19},

journal = {Clocks & Sleep},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{katsouri2020ablation,

title = {Ablation of reactive astrocytes exacerbates disease pathology in a model of Alzheimer's disease},

author = {Loukia Katsouri and Amy M Birch and Alexander WJ Renziehausen and Carolin Zach and Yahyah Aman and Hannah Steeds and Angela Bonsu and Emily OC Palmer and Nazanin Mirzaei and Miriam Ries and others},

year  = {2020},

date = {2020-01-01},

journal = {Glia},

volume = {68},

number = {5},

pages = {1017--1030},

publisher = {John Wiley & Sons, Inc. Hoboken, USA},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Thiesse2019,

title = {Transportation noise impairs cardiovascular function without altering sleep: the importance of autonomic arousals},

author = {L Thiesse and F Rudzik and JF Krämer and K Spiegel and R Leproult and N Wessel and R Pieren and H Héritier and IC Eze and M Foraster and C Garbazza and D Vienneau and M Brink and JM Wunderli and N Probst-Hensch and M Röösli and C Cajochen},

doi = {10.1016/j.envres.2019.109086},

year  = {2019},

date = {2019-12-30},

journal = {Environ Res},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Spitschan2019d,

title = {No evidence for an S cone contribution to acute neuroendocrine and alerting responses to light},

author = {M. Spitschan and R. Lazar and E. Yetik and C. Cajochen },

url = {https://www.cell.com/current-biology/fulltext/S0960-9822(19)31501-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0960982219315015%3Fshowall%3Dtrue},

doi = {10.1016/j.cub.2019.11.031},

year  = {2019},

date = {2019-12-16},

journal = {Current Biology},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Blume2019bb,

title = {“How does Austria sleep?” self-reported sleep habits and complaints in an online survey},

author = {C Blume and T Hauser and T Winkler and PJ D Heib and WR. Gruber and M Schabus},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/01/Blume2019_Article_HowDoesAustriaSleepSelf-report.pdf},

doi = {10.1007/s11325-019-01982-5},

year  = {2019},

date = {2019-12-14},

journal = {Sleep Breath},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Cajochen2019bb,

title = {Evidence That Homeostatic Sleep Regulation Depends on Ambient Lighting Conditions during Wakefulness},

author = {C Cajochen and C F Reichert and M Maire and L J M Schlangen and C Schmidt and A U Viola and V Gabel},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/05/clockssleep-01-00040-v2.pdf},

doi = {10.3390/clockssleep1040040},

year  = {2019},

date = {2019-12-11},

journal = {Clocks & Sleep},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Garbazza2019c,

title = {Polysomnographic features of pregnancy: A systematic review},

author = {C Garbazza and S Hackethal and S Riccardi and C Cajochen and A Cicolin and A D'Agostino and F Cirignotta and M Manconi},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/01/1-s2.0-S1087079219302175-main.pdf},

doi = {10.1016/j.smrv.2019.101249},

year  = {2019},

date = {2019-12-05},

journal = {Sleep Med Rev.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Spitschan2019f,

title = {Visual and non-visual properties of filters manipulating short-wavelength light},

author = {M. Spitschan and R. Lazar and C. Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/01/Spitschan_et_al-2019-Ophthalmic_and_Physiological_Optics-1.pdf},

doi = {10.1111/opo.12648},

year  = {2019},

date = {2019-11-01},

journal = {Ophthalmic Physiol Opt},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Spitschan2019bb,

title = {Binocular facilitation in light-mediated melatonin suppression?},

author = {M Spitschan and C Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/01/Spitschan_et_al-2019-Journal_of_Pineal_Research.pdf},

doi = {10.1111/jpi.12602},

year  = {2019},

date = {2019-11-01},

journal = {J Pineal Res},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Four minutes might not be enough for color temperature of light to affect subjective sleepiness, mental effort, and light ratings},

author = {R Lasauskaite and E M Hazelhoff and C. Cajochen},

doi = {10.1177/1477153518796700},

year  = {2019},

date = {2019-11-01},

urldate = {2019-11-01},

journal = {Lighting Research & Technology},

volume = {51},

issue = {7},

pages = {1128–1138},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Brink2019bb,

title = {Self-Reported Sleep Disturbance from Road, Rail and Aircraft Noise: Exposure-Response Relationships and Effect Modifiers in the SiRENE Study},

author = {M Brink and B Schäffer and D Vienneau and R Pieren and M Foraster and I C Eze and F Rudzik and L Thiesse and C Cajochen and N Probst-Hensch and M Röösli and Wunderli J M JM24.},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/01/ijerph-16-04186-v3.pdf},

doi = {10.3390/ijerph16214186},

year  = {2019},

date = {2019-10-29},

journal = {Environ Int},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Röösli2019b,

title = {Associations of Various Nighttime Noise Exposure Indicators with Objective Sleep Efficiency and Self-Reported Sleep Quality: A Field Study},

author = {M Röösli and M Brink and F Rudzik and C Cajochen and M S Ragettli and B Flückiger and R Pieren and D Vienneau and J -M Wunderli},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/01/ijerph-16-03790.pdf},

doi = {10.3390/ijerph16203790},

year  = {2019},

date = {2019-10-09},

journal = {Environ Int},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Aderneuer2019b,

title = {Circadian tuning with metameric white light: Visual and non-visual aspects},

author = {T Aderneuer and O Stefani and O Fernandez and C Cajochen and R Ferrini},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/preprints201909.0227.v1.pdf},

doi = {10.20944/preprints201909.0227.v1},

year  = {2019},

date = {2019-09-19},

keywords = {},

pubstate = {forthcoming},

tppubtype = {article}

}

@article{Blume2019d,

title = {Effects of light on human circadian rhythms, sleep and mood},

author = {C Blume and C Garbazza and M Spitschan},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/01/EMS84169.pdf},

doi = {doi:10.1007/s11818-019-00215-x},

year  = {2019},

date = {2019-09-18},

journal = {Somnologie Berl},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Knoop2019b,

title = {Daylight: What makes the difference?},

author = {M Knoop and O Stefani and B Bueno and B Matusiak and R Hobday and A Wirz-Justice and K Martiny and T Kantermann and M P J Aarts and N Zemmouri and S Appeltk and B Norton},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/03/1477153519869758.pdf},

doi = {10.1177/1477153519869758},

year  = {2019},

date = {2019-08-18},

journal = {Lighting Research & Technology},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Miano2019b,

title = {Shooting a high-density electroencephalographic picture on sleep in children with attention-deficit/hyperactivity disorder},

author = {S Miano and N Amato and C Garbazza and M Abbafati and G Foderaro and V Pezzoli and G P Ramelli and M Manconi},

doi = {10.1093/sleep/zsz167},

year  = {2019},

date = {2019-07-29},

journal = {Sleep},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Spitschan2019cb,

title = {How to Report Light Exposure in Human Chronobiology and Sleep Research Experiments},

author = {M Spitschan and O Stefani and P Blattner and C Gronfier and S W Lockley and R J Lucas},

url = {http://www.chronobiology.ch/wp-content/uploads/2020/01/EMS83534.pdf},

doi = {10.3390/clockssleep1030024},

year  = {2019},

date = {2019-07-01},

journal = {Clocks Sleep},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Bromundt2019bb,

title = {Effects of a dawn-dusk simulation on circadian rest-activity cycles, sleep, mood and well-being in dementia patients},

author = {V Bromundt and A Wirz-Justice and M Boutellier and S Winter and M Haberstroh and M Termane and M Münch},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/08/Bromundt-DDS-Exp-Gerontology-2019.pdf},

doi = {10.1016/j.exger.2019.110641},

year  = {2019},

date = {2019-06-25},

journal = {Experimental Gerontology},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Garbazza2019bb,

title = {Measuring and interpreting periodic leg movements during sleep: easy does it},

author = {C Garbazza and S Hackethal},

doi = {10.1093/sleep/zsz155},

year  = {2019},

date = {2019-06-18},

journal = {Sleep},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Gaig2019b,

title = {Characterization of the sleep disorder of anti-IgLON5 disease.},

author = {C Gaig and A Iranzo and C Cajochen and I Vilaseca and C Embid and J Dalmau and F Graus and J Santamaria},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/06/zsz133.pdf},

doi = {10.1093/sleep/zsz133},

year  = {2019},

date = {2019-06-14},

journal = {Sleep},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Roenneberg2019b,

title = {Why Should We Abolish Daylight Saving Time?},

author = {T Roenneberg and A Wirz-Justice and D J Skene and S Ancoli-Israel and K P Wright and D -J Dijk and P Zee and M R Gorman and E C Winnebeck and E B Klerman},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/08/JBR-DST.pdf},

doi = {10.1177/0748730419854197},

year  = {2019},

date = {2019-06-06},

journal = {Journal of Biological Rhythms},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Chellappa2019b,

title = {Association of Intraocular Cataract Lens Replacement With Circadian Rhythms, Cognitive Function, and Sleep in Older Adults},

author = {SL. Chellappa and V Bromundt and S Frey and A Steinemann and C Schmidt and T Schlote and D Goldblum and C Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/jamaophthalmology_chellappa_2019_oi_190029.pdf},

doi = {10.1001/jamaophthalmol.2019.1406},

year  = {2019},

date = {2019-05-23},

journal = {JAMA Ophthalmol},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Zhang2019b,

title = {Social Jetlag and Chronotypes in the Chinese Population: Analysis of Data Recorded by Wearable Devices},

author = {Z Zhang and C Cajochen and R Khatami},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/06/fb5f17f5-08cb-47d2-885d-25b22fea372a.pdf},

doi = {10.2196/13482},

year  = {2019},

date = {2019-05-11},

journal = {J Med Internet Res},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Pollmann2019b,

title = {How to Work in the Car of the Future?: A Neuroergonomical Study Assessing Concentration, Performance and Workload Based on Subjective, Behavioral and Neurophysiological Insights.},

author = {K Pollmann and O Stefani and A Bengsch and M Peissner and M Vukeli?},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/paper054.pdf},

doi = {10.1145/3290605.3300284},

isbn = {978-1-4503-5970-2},

year  = {2019},

date = {2019-05-04},

booktitle = {Proceedings of the 2019 CHI Conference on Human Factors in Computing Systems},

issuetitle = {CHI '19},

pages = {14},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Knaier2019bb,

title = {Which Cutoffs for Secondary V?O2max Criteria Are Robust to Diurnal Variations?},

author = {R Knaier and M Niemeyer and J Wagner and D Infanger and T Hinrichs and C Klenk and S Frutig and C Cajochen and A Schmidt-Trucksäss},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/application-pdf.pdf},

doi = {10.1249/MSS.0000000000001869},

year  = {2019},

date = {2019-05-01},

journal = {Med Sci Sports Exerc.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Brink2019d,

title = {A survey on exposure-response relationships for road, rail, and aircraft noise annoyance: Differences between continuous and intermittent noise.},

author = {M Brink and B Schäffer and D Vienneau and M Foraster and R Pieren and IC. Eze and C Cajochen and N Probst-Hensch and M Röösli and JM. Wunderli},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/1-s2.0-S016041201831897X-main.pdf},

doi = {10.1016/j.envint.2019.01.043},

year  = {2019},

date = {2019-04-01},

journal = {Environ Int},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Steinemann2019b,

title = {Evaluation of Visual Comfort and Mental Effort Under Different Light Conditions for Ultraviolet-Absorbing and Additional Blue-Filtering Intraocular Lenses for Cataract Surgery.},

author = {A Steinemann and V Bromundt and SL. Chellappa and S Frey and C Schmidt and T Schlote and D Goldblum and C Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/a-0810-0302.pdf},

doi = {10.1055/a-0810-0302},

year  = {2019},

date = {2019-04-01},

journal = {Klin Monbl Augenheilkd.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Cajochen2019d,

title = {Effect of daylight LED on visual comfort, melatonin, mood, waking performance and sleep},

author = {C Cajochen and M Freyburger and T Basishvili and C Garbazza and F Rudzik and C Renz and K Kobayashi and Y Shirakawa and O Stefani and J Weibel},

doi = {10.1177/1477153519828419},

year  = {2019},

date = {2019-03-24},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Knaier2019d,

title = {In Athletes, the Diurnal Variations in Maximum Oxygen Uptake Are More Than Twice as Large as the Day-to-Day Variations.},

author = {R Knaier and D Infanger and M Niemeyer and C Cajochen and A Schmidt-Trucksäss},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/fphys-10-00219.pdf},

doi = {10.3389/fphys.2019.00219},

year  = {2019},

date = {2019-03-18},

journal = {Front Physiol.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Vienneau2019b,

title = {Façades, floors and maps - Influence of exposure measurement error on the association between transportation noise and myocardial infarction.},

author = {D Vienneau and H Héritier and M Foraster and IC. Eze and E Schaffner and L Thiesse and F Rudzik and M Habermacher and M Köpfli and R Pieren and M Brink and C Cajochen and JM. Wunderli and N Probst-Hensch and M Röösli and SNC study group},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/1-s2.0-S0160412018317422-main.pdf},

doi = {10.1016/j.envint.2018.12.015},

year  = {2019},

date = {2019-02-01},

journal = {Environ Int.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Héritier2019b,

title = {A systematic analysis of mutual effects of transportation noise and air pollution exposure on myocardial infarction mortality: a nationwide cohort study in Switzerland.},

author = {H Héritier and D Vienneau and M Foraster and IC. Eze and E Schaffner and K de Hoogh and L Thiesse and F Rudzik and M Habermacher and M Köpfli and R Pieren and M Brink and C Cajochen and JM. Wunderli and N Probst-Hensch and M Röösli},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/ehy650.pdf},

doi = {10.1093/eurheartj/ehy650},

year  = {2019},

date = {2019-02-01},

journal = {Eur Heart J.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wirz-Justice2019b,

title = {Perspectives in affective disorders: Clocks and sleep.},

author = {A Wirz-Justice and F Benedetti},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/Perspectives-in-affective-disorders-EJN-2019.pdf},

doi = {10.1111/ejn.14362},

year  = {2019},

date = {2019-01-31},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Schneeberger2019b,

title = {Differences in Insomnia Symptoms between Immigrants and Non-Immigrants in Switzerland attributed to Emotional Distress: Analysis of the Swiss Health Survey.},

author = {AR. Schneeberger and A Seixas and N Schweinfurth and UE. Lang and C Cajochen and DA. Bux and S Richards and Jean-Louis and CG. Huber},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/ijerph-16-00289.pdf},

doi = {10.3390/ijerph16020289},

year  = {2019},

date = {2019-01-21},

journal = {Int J Environ Res Public Health},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Hug2019b,

title = {Later Chronotype Is Associated with Higher Alcohol Consumption and More Adverse Childhood Experiences in Young Healthy Women},

author = {E Hug and K Winzeler and M C Pfaltz and C Cajochen and K Bader},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/clockssleep-01-00012.pdf},

doi = {10.3390/clockssleep1010012},

year  = {2019},

date = {2019-01-12},

journal = {Clocks Sleep},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Benedetti2019bb,

title = {Impact of dynamic lighting control on light exposure, visual comfort and alertness in office users},

author = {M Benedetti and L Maierová and C Cajochen and A Motamed and M Münch and J-L Scartezzini},

url = {http://www.chronobiology.ch/wp-content/uploads/2021/09/Benedetti_2019_J._Phys.__Conf._Ser._1343_012160.pdf},

doi = {10.1088/1742-6596/1343/1/012160},

year  = {2019},

date = {2019-01-01},

journal = {J. Phys.: Conf. Ser.},

abstract = {The lighting environment at indoor workplaces is important not only to provide vision and visual comfort, but also for light's direct influence on human physiology, cognitive performance and mood. The purpose of this ongoing study is to investigate the impact of a dynamic control of combined daylight and artificial lighting on office users' visual comfort as well as on alertness and cognitive performance. We are going to evaluate the impact of two different office lighting conditions in a quasi-real setting on subjective alertness ratings in healthy young participants over several days. We will compare an office with optimized daylighting and artificial lighting, operated by a new control system with a standard office room, where the lighting/shading can be changed manually. The aim of this balanced crossover within study design is to show that exposure to optimized dynamic lighting control over several days is superior on subjective alertness and glare indexes, when compared to a conventional lighting control. Here, we present some preliminary results from the first six participants on the comparison of subjective evaluations of alertness and the objective monitored (day-) light exposures and glare index Daylight Glare Probability (DGP) in the two different conditions over one week (five days) each.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{ma2019rapid,

title = {Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain},

author = {Qiaoli Ma and Miriam Ries and Yann Decker and Andreas Müller and Chantal Riner and Arno Bücker and Klaus Fassbender and Michael Detmar and Steven T Proulx},

year  = {2019},

date = {2019-01-01},

journal = {Acta neuropathologica},

volume = {137},

number = {1},

pages = {151--165},

publisher = {Springer Berlin Heidelberg},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{bachmann2019differential,

title = {Differential effects of anaesthesia on the contractility of lymphatic vessels in vivo},

author = {Samia B Bachmann and Steven T Proulx and Yuliang He and Miriam Ries and Michael Detmar},

year  = {2019},

date = {2019-01-01},

journal = {The journal of physiology},

volume = {597},

number = {11},

pages = {2841--2852},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Thiesse2018b,

title = {Adverse impact of nocturnal transportation noise on glucose regulation in healthy young adults: Effect of different noise scenarios.},

author = {L Thiesse and F Rudzik and K Spiegel and R Leproult and R Pieren and JM. Wunderli and M Foraster and H Héritier and IC. Eze and M Meyer and D Vienneau and M Brink and N Probst-Hensch and M Röösli and C Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/1-s2.0-S0160412018304252-main.pdf},

doi = {10.1016/j.envint.2018.05.036},

year  = {2018},

date = {2018-12-01},

journal = {Environ Int.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Khan2018b,

title = {Circadian rhythm and epilepsy.},

author = {S Khan and L Nobili and R Khatami and T Loddenkemper and C Cajochen and DJ. Dijk and SH. Eriksson},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/1-s2.0-S1474442218303351-main.pdf},

doi = {10.1016/S1474-4422(18)30335-1},

year  = {2018},

date = {2018-12-01},

journal = {Lancet Neurol.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Foraster2018b,

title = {Long-term exposure to transportation noise and its association with adiposity markers and development of obesity.},

author = {M Foraster and IC. Eze and D Vienneau and E Schaffner and A Jeong and H Héritier and F Rudzik and L Thiesse and R Pieren and M Brink and C Cajochen and JM. Wunderli and M Röösli and N Probst-Hensch},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/1-s2.0-S0160412018312406-main.pdf},

doi = {10.1016/j.envint.2018.09.057},

year  = {2018},

date = {2018-12-01},

journal = {Environ Int.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Eze2018b,

title = {Transportation noise exposure, noise annoyance and respiratory health in adults: A repeated-measures study.},

author = {IC. Eze and M Foraster and E Schaffner and D Vienneau and H Héritier and R Pieren and L Thiesse and F Rudzik and T Rothe and M Pons and R Bettschart and C Schindler and C Cajochen and JM. Wunderli and M Brink and M Röösli and N Probst-Hensch},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/1-s2.0-S0160412018315939-main.pdf},

doi = {10.1016/j.envint.2018.10.006},

year  = {2018},

date = {2018-12-01},

journal = {Environ Int.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Management Strategies for Restless Legs Syndrome/Willis-Ekbom Disease During Pregnancy.},

author = {C Garbazza and M Manconi},

year  = {2018},

date = {2018-09-13},

journal = {Sleep Medicine Clinics},

pages = {doi: 10.1016/j.jsmc.2018.05.001},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Chronobiologie: Von der Pünktlichkeit des Lebens},

author = {M Meyer},

url = {http://www.chronobiology.ch/wp-content/uploads/2018/10/M.Meyer_.pdf},

year  = {2018},

date = {2018-09-01},

journal = {Zaenmagazin},

volume = {3},

pages = {43-46},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Genetic Factors Affecting Seasonality, Mood, and the Circadian Clock.},

author = {C Garbazza and F Benedetti},

url = {http://www.chronobiology.ch/wp-content/uploads/2018/09/fendo-09-00481-1.pdf},

year  = {2018},

date = {2018-08-23},

journal = {Frontiers in Endocrinology},

pages = {doi: 10.3389/fendo.2018.00481},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Non-24-Hour Sleep-Wake Disorder in Sighted Patients: Dealing With an Orphan Disease.},

author = {C Garbazza},

url = {http://www.chronobiology.ch/wp-content/uploads/2018/09/Article.pdf},

year  = {2018},

date = {2018-08-15},

journal = {Journal of Clinical Sleep Medicine},

pages = {doi: 10.5664/jcsm.7304},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Exploiting metamerism to regulate the impact of a visual display on alertness and melatonin suppression independent of visual appearance.},

author = {A E Allen and E M Hazelhoff and F P Martial and C Cajochen and R J Lucas},

url = {http://www.chronobiology.ch/wp-content/uploads/2018/09/zsy100.pdf},

year  = {2018},

date = {2018-08-01},

journal = {Sleep},

volume = {41},

number = {8},

pages = {doi: 10.1093/sleep/zsy100},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wirz-Justice2018bb,

title = {Prevalence of seasonal depression in a prospective cohort study.},

author = {A Wirz-Justice and V Ajdacic and W Rössler and HC. Steinhausen and J Angst},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/Wirz-Justice-Angst-2018-EurJPsychClinNeurosci.pdf},

doi = {10.1007/s00406-018-0921-3},

year  = {2018},

date = {2018-07-18},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{vanderMeijden2018b,

title = {Sustained effects of prior red light on pupil diameter and vigilance during subsequent darkness.},

author = {WP. van der Meijden and BHW. Te Lindert and JR. Ramautar and Y Wei and JE. Coppens and M Kamermans and C Cajochen and Bourgin EJW. Van P Someren},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/rspb.2018.0989.pdf},

doi = {10.1098/rspb.2018.0989},

year  = {2018},

date = {2018-07-18},

journal = {Proc Biol Sci.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Sleep spindle characteristics and arousability from nighttime transportation noise exposure in healthy young and older individuals.},

author = {F Rudzik and L Thiesse and R Pieren and J M Wunderli and M Brink and M Foraster and H Héritier and I C Exe and C Garbazza and D Vienneau and N Probst-Hensch and M Röösli and C Cajochen},

year  = {2018},

date = {2018-07-01},

journal = {Sleep},

volume = {41},

number = {7},

pages = {doi: 10.1093/sleep/zsy077},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Sheaves2018b,

title = {Stabilising sleep for patients admitted at acute crisis to a psychiatric hospital (OWLS): an assessor-blind pilot randomised controlled trial.},

author = {B Sheaves and D Freeman and L Isham and J McInerney and A Nickless and L Yu and S Rek and J Bradley and S Reeve and C Attard and C Espie and R Foster and A Wirz-Justice and E Chadwick and A Barrera},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/S0033291717003191a.pdf},

doi = {10.1017/S0033291717003191},

year  = {2018},

date = {2018-07-01},

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}

@article{,

title = {Leg Movement Activity During Sleep in Adults With Attention-Deficit/Hyperactivity Disorder.},

author = {C Garbazza and C Sauter and J Paul and J Kollek and C Dujardin and S Hackethal and H Dorn and A Peter and M L Hansen and M Manconi and R Ferri and H Danker-Hopfe},

url = {http://www.chronobiology.ch/wp-content/uploads/2018/09/fpsyt-09-00179.pdf},

year  = {2018},

date = {2018-05-04},

journal = {Frontiers in Psychiatry},

pages = {doi: 10.3389/fpsyt.2018.00179},

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}

@article{,

title = {Morning bright light exposure has no influence on self-chosen exercise intensity and mood in overweight individuals - A randomized controlled trial.},

author = {R Knaier and C Klenk and K Königstein and T Hinrichs and A Rossmeissl and D Infanger and C Cajochen and A Schmidt-Trucksäss},

isbn = {doi: 10.1080/07420528.2017.1414828.},

year  = {2018},

date = {2018-04-01},

journal = {Chronobiology International},

volume = {35},

number = {4},

pages = {477-485},

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pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Diurnal variability of transportation noise exposure and cardiovascular mortality: A nationwide cohort study from Switzerland.},

author = {H Héritier and D Vienneau and M Foraster and I C Exe and E Schaffner and L Thiesse and F Rzudik and M Habermacher and M Köpfli and R Pieren and A Schmidt-Trucksäss and M Brink and C Cajochen and J M Wunderli and N Probst-Hensch and M Röösli and SNC Study Group},

isbn = {doi: 10.1016/j.ijheh.2018.02.005},

year  = {2018},

date = {2018-04-01},

journal = {International Journal of Hygiene and Environmental Health},

volume = {221},

number = {3},

pages = {556-563},

keywords = {},

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}

@article{,

title = {„Gutes“ Blaulicht, „schlechtes“ Blaulicht – geblockt wird, was krank macht},

author = {O Stefani},

editor = {Benjamin Editor},

url = {http://www.chronobiology.ch/wp-content/uploads/2018/10/Blaufilter-in-Brillengla?sern-DOZ-0420182.pdf},

year  = {2018},

date = {2018-04-01},

journal = {Deutsche Optiker Zeitung},

volume = {4},

pages = {58-60},

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@article{,

title = {Ist Blaulicht gefährlich?},

author = {O Stefani and A Pross},

url = {http://www.chronobiology.ch/wp-content/uploads/2018/10/Blaulichtgefaehrdung-SAFETY-PLUS-3-18.pdf},

year  = {2018},

date = {2018-03-01},

journal = {Safety-Plus Schweizer Fachzeitschrift für Arbeitssicherheit und Gesundheitsschutz},

volume = {3},

pages = {24-27},

keywords = {},

pubstate = {published},

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}

@article{,

title = {Influence of lighting color temperature on effort-related cardiac response},

author = {R Lasauskaite and C. Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2017/11/1-s2.0-S0301051117303186-main.pdf},

year  = {2018},

date = {2018-02-01},

urldate = {2018-02-01},

journal = {Biological Psychology},

volume = {132},

pages = {doi:10.1016/j.biopsycho.2017.11.005},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{Wirz-Justice2018d,

title = {Does anaesthesia stop the clock?},

author = {A Wirz-Justice and M Frank},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/05/WJFrank-SMR-Anaesthesia.pdf},

doi = {10.1016/j.smrv.2017.06.004},

year  = {2018},

date = {2018-02-01},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Human brain patterns underlying vigilant attention: impact of sleep debt, circadian phase and attentional engagement.},

author = {M Maire and C F Reichert and V Gabel and A U Viola and C Phillips and C Berthomier and S Borgwardt and C Cajochen and C Schmidt},

url = {http://www.chronobiology.ch/wp-content/uploads/2018/09/s41598-017-17022-9.pdf},

year  = {2018},

date = {2018-01-17},

journal = {Scientific Reports},

pages = {doi: 10.1038/s41598-017-17022-9},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{ijerph15010149b,

title = {Differences between Outdoor and Indoor Sound Levels for Open, Tilted, and Closed Windows},

author = {Barbara Locher and André Piquerez and Manuel Habermacher and Martina Ragettli and Martin Röösli and Mark Brink and Christian Cajochen and Danielle Vienneau and Maria Foraster and Uwe Müller and Jean Marc Wunderli},

url = {http://www.mdpi.com/1660-4601/15/1/149},

issn = {1660-4601},

year  = {2018},

date = {2018-01-01},

journal = {International Journal of Environmental Research and Public Health},

volume = {15},

number = {1,149},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Chronobiology comes of age},

author = {A Wirz-Justice},

url = {http://onlinelibrary.wiley.com/doi/10.1111/acps.12828/epdf},

year  = {2017},

date = {2017-12-01},

journal = {Acta Psychiatrica Scandinavica},

volume = {136},

number = {6},

pages = {531–533. doi:10.1111/acps.12828},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Exposure to night-time traffic noise, melatonin-regulating gene variants and change in glycemia in adults},

author = {I C Eze and M Imboden and M Foraster and E Schaffner and A Kumar and D Vienneau and H Hériter and F Rudzik and L Thiesse and R Pieren and A von Eckardstein and C Schindler and M Brink and J -M Wunderli and C Cajochen and M Röösli and N Probst-Hensch},

url = {http://www.chronobiology.ch/wp-content/uploads/2017/11/ijerph-245694-final.pdf},

year  = {2017},

date = {2017-11-29},

journal = {International Journal of Environmental Research and Public Health},

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pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Mit "inneren Rhythmen" zum Nobelpreis},

author = {C Garbazza},

url = {http://www.chronobiology.ch/wp-content/uploads/2018/09/Mit-inneren-Rhythmen-zum-Nobelpreis.pdf},

year  = {2017},

date = {2017-11-10},

journal = {Psychiatrie & Neurologie},

volume = {5},

pages = {1},

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pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Innere Uhr und psychische Gesundheit},

author = {C Garbazza and C Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2018/09/Innere-Uhr-und-psychische-Gesundheit.pdf},

year  = {2017},

date = {2017-11-10},

journal = {Psychiatrie & Neurologie},

volume = {5},

pages = {4},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Sex differences in light sensitivity impact on brightness perception, vigilant attention and sleep in humans},

author = {S. L. Chellappa and R. Steiner and P. Oelhafen and C. Cajochen},

url = {https://www.nature.com/articles/s41598-017-13973-1.pdf},

year  = {2017},

date = {2017-10-27},

journal = {Scientific Reports},

volume = {7},

number = {14215},

pages = {doi:10.1038/s41598-017-13973-1},

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}

@article{,

title = {In a Heartbeat: Light and Cardiovascular Physiology},

author = {S L Chellappa and R Lasauskaite and C. Cajochen},

url = {http://www.chronobiology.ch/wp-content/uploads/2017/10/fneur-08-00541.pdf},

year  = {2017},

date = {2017-10-20},

urldate = {2017-10-20},

journal = {Frontiers in Neurology},

volume = {8},

pages = {doi:10.3389/fneur.2017.00541},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Seasonality in affective disorders},

author = {A. Wirz-Justice},

url = {http://www.chronobiology.ch/wp-content/uploads/2017/10/1-s2.0-S001664801730237X-main.pdf},

year  = {2017},

date = {2017-10-06},

journal = {General and Comparative Endocrinology},

pages = {doi:10.1016/j.ygcen.2017.07.010},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Exposure to road, railway, and aircraft noise and arterial stiffness in the SAPALDIA Study: Annual average noise levels and temporal noise characteristics},

author = {M. Foraster and I. C. Eze and E. Schaffner and D. Vienneau and H. Héritier and S. Endes and F. Rudzik and L. Thiesse and R. Pieren and C. Schindler and A. Schmidt-Trucksäss and M. Brink and C. Cajochen and J. M. Wunderli and M. Röösli and N. Probst-Hensch},

url = {https://ehp.niehs.nih.gov/wp-content/uploads/2017/09/EHP1136.alt_.pdf},

year  = {2017},

date = {2017-09-07},

journal = {Environmental Health Perspectives},

volume = {125},

number = {9},

pages = {doi:10.1289/EHP1136},

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pubstate = {published},

tppubtype = {article}

}

@article{,

title = {Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness},

author = {V. Gabel and C. F. Reichert and M. Maire and C. Schmidt and L. J. M. Schlangen and V. Kolodyazhniy and C. Garbazza and C. Cajochen and A. U. Viola},

url = {https://www.nature.com/articles/s41598-017-07060-8.pdf},

year  = {2017},

date = {2017-08-08},

journal = {Scientific Reports},

volume = {7},

number = {7620},

pages = {doi:doi:10.1038/s41598-017-07060-8},

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}

@article{,

title = {Effects of bright and blue light on acoustic reaction time and maximum handgrip strength in male athletes: a randomized controlled trial},

author = {R. Knaier and J. Schäfer and A. Rossmeissl and C. Klenk and H. Hanssen and C. Höchsmann and C. Cajochen and A. Schmidt-Trucksäss},

year  = {2017},

date = {2017-08-01},

journal = {European Journal of Applied Physiology},

volume = {117},

number = {8},

pages = {1689–1696},

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title = {Cognitive brain responses during circadian wake-promotion: evidence for sleep-pressure-dependent hypothalamic activations},

author = {C. F. Reichert and M. Maire and V. Gabel and A. U. Viola and T. Götz and K. Scheffler and M. Klarhöfer and C. Berthomier and W. Strobel and C. Phillips and E. Salmon and C. Cajochen and C. Schmidt},

url = {http://www.chronobiology.ch/wp-content/uploads/2019/03/Reichert_et_al-2017-Scientific_Reports_Cognitive-brain-responses.pdf},

year  = {2017},

date = {2017-07-17},

journal = {Scientific Reports},

volume = {7},

pages = {doi:10.1038/s41598-017-05695-1},

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@article{,

title = {Bright light delights: effects of daily light exposure on emotions, rest-activity cycles, sleep and melatonin secretion in severely demented patients},

author = {M Münch and M Schmieder and K Bieler and R Goldbach and T Fuhrmann and N Zumstein and P Vonmoos and J L Scartezzini and A Wirz-Justice and Cajochen C .},

year  = {2017},

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journal = {Current Alzheimer Research},

volume = {14},

pages = {doi:10.2174/1567205014666170523092858},

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@article{,

title = {Prime time light exposures do not seem to improve maximal physical performance in male elite athletes, but enhance end-spurt performance},

author = {R. Knaier and J. Schäfer and A. Rossmeissl and C. Klenk and H. Hanssen and C. Höchsmann and C. Cajochen and A Schmidt-Trucksäss},

year  = {2017},

date = {2017-05-01},

journal = {Frontiers in Psysiology},

pages = {doi:10.3389/fphys.2017.00264},

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}